{"id":"W2087757426","doi":"10.1074/jbc.m709906200","title":"Solute Carrier 11 Cation Symport Requires Distinct Residues in Transmembrane Helices 1 and 6","year":2008,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Trace Elements in Health","field":"Nursing","cited_by":45,"is_retracted":false,"has_abstract":true,"ca_institutions":"Armand Frappier Museum; Institut National de la Recherche Scientifique","funders":"Canadian Institutes of Health Research; Grantová Agentura České Republiky; Armand-Frappier Foundation","keywords":"Symporter; Transmembrane protein; Transmembrane domain; Chemistry; Biophysics; Transporter; Biochemistry; Membrane; Biology; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004535277,0.0001226619,0.0002828005,0.00003222045,0.00009250828,0.00001124904,0.0001433389,0.0001682109,0.00008358341],"category_scores_gemma":[0.000259852,0.0000884366,0.00005733431,0.00009319175,0.0001784659,0.0001245689,0.00001736849,0.0003074334,4.610268e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009265675,"about_ca_system_score_gemma":0.00004581752,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006793074,"about_ca_topic_score_gemma":0.00004102486,"domain_scores_codex":[0.9987295,0.00006311951,0.0006103979,0.0001696434,0.0001949096,0.0002324371],"domain_scores_gemma":[0.9992309,0.0001580511,0.0003189885,0.0001032639,0.00006344313,0.0001253947],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0004886855,0.0001506231,0.7707058,0.0001717017,0.00001489537,0.0001571196,0.0005666895,0.0000108751,0.224786,0.000003409761,0.0004186706,0.002525531],"study_design_scores_gemma":[0.0009249748,0.0002784667,0.823642,0.0001620151,0.00001696092,0.0007635636,0.0002167649,0.00001562468,0.1711108,0.000208175,0.002492244,0.0001683293],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.996587,0.001321168,0.00001326638,0.001548312,0.0001399853,0.00006242353,0.00001084802,0.00001534764,0.0003016913],"genre_scores_gemma":[0.9986519,0.0004333177,0.0004280935,0.0001002067,0.0003204021,0.000002213526,0.00000624512,0.000007468966,0.00005019367],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0536752,"threshold_uncertainty_score":0.360634,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04690173353089985,"score_gpt":0.3089565374754296,"score_spread":0.2620548039445297,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}