{"id":"W2087762541","doi":"10.1081/ncn-100002520","title":"EFFECT OF SUBSTITUTING ARABINONUCLEOSIDES FOR DEOXYNUCLEOTIDES IN THE DNA PRIMING STRAND ON THE POLYMERASE ACTION OF HIV-1 RT","year":2001,"lang":"en","type":"article","venue":"Nucleosides Nucleotides & Nucleic Acids","topic":"HIV/AIDS drug development and treatment","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"Primer (cosmetics); DnaG; DNA; DNA polymerase; DNA clamp; DNA polymerase II; Primase; Molecular biology; Polymerase; Biology; DNA replication; DNA synthesis; Chemistry; Polymerase chain reaction; Genetics; Circular bacterial chromosome; Reverse transcriptase; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005128683,0.0004993268,0.0004209322,0.0001195035,0.0001325688,0.0004553602,0.0003287058,0.0003922076,0.001415142],"category_scores_gemma":[0.001032291,0.0003186776,0.0001540925,0.0001675997,0.0003437451,0.0002852483,0.000182737,0.0005161074,0.0003154712],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001928679,"about_ca_system_score_gemma":0.000363799,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005626954,"about_ca_topic_score_gemma":0.000744423,"domain_scores_codex":[0.999643,0.0001596637,0.00003954261,0.00006041391,0.00004373284,0.00005367107],"domain_scores_gemma":[0.9991068,0.000528782,0.0001311564,0.00007745003,0.00004112677,0.0001147499],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001745627,0.0001221627,0.0004543625,0.0001153598,0.00002526741,0.0002205756,0.00008162254,0.0007320629,0.9919412,0.0002623778,0.00003633583,0.004262981],"study_design_scores_gemma":[0.00002778591,0.00105745,0.0004028725,0.000007790356,0.0000256021,0.0001511242,0.00001668129,0.0004931853,0.9967977,0.00003028437,0.0009835464,0.000006010753],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9969447,0.00134386,0.0005358254,0.00003611093,0.00002748692,0.00001866885,0.00006651027,0.00002687737,0.001000016],"genre_scores_gemma":[0.9963151,0.0007116272,0.002107988,0.00003466394,0.00001015929,0.00001063133,0.0001054289,0.00002020318,0.0006841802],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001415142,"threshold_uncertainty_score":0.004734099,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02584565512606374,"score_gpt":0.2933488589747745,"score_spread":0.2675032038487107,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}