{"id":"W2087769083","doi":"10.4161/cc.20946","title":"Toward an integrative view of Optineurin functions","year":2012,"lang":"en","type":"review","venue":"Cell Cycle","topic":"S100 Proteins and Annexins","field":"Biochemistry, Genetics and Molecular Biology","cited_by":94,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Institute of Cancer Research; Institut National Du Cancer; Centre National de la Recherche Scientifique","keywords":"Optineurin; Biology; Amyotrophic lateral sclerosis; Disease; Cell biology; Computational biology; Neuroscience; Mutation; Genetics; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001030723,0.0002529582,0.0005466549,0.00004276335,0.00003528763,0.00001038674,0.0002349273,0.0002570678,0.0001450952],"category_scores_gemma":[0.00001117991,0.0001878949,0.0003336042,0.00009083239,0.00005684039,0.000003513895,0.0001083083,0.0001535966,0.00006167776],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000009533745,"about_ca_system_score_gemma":0.0001013881,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001699558,"about_ca_topic_score_gemma":0.000007854648,"domain_scores_codex":[0.9990577,0.00009741463,0.0002857847,0.0003004168,0.0000664203,0.0001922987],"domain_scores_gemma":[0.9992134,0.000007249648,0.0001865699,0.0004484313,0.00004870059,0.00009564174],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000004960449,0.0002230711,0.000002226616,0.00384548,0.00006515762,0.000001387852,0.00003677426,0.000001083659,0.001672052,0.00004127769,0.0004580614,0.9936485],"study_design_scores_gemma":[0.00006815926,0.0001954425,0.000001822686,0.0005501704,0.0001897954,0.000008906655,0.00004037013,7.011765e-7,0.002098156,0.000005425776,0.9966378,0.000203267],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0003052012,0.9920073,0.0002640034,0.000002433011,0.0001799452,0.0003150141,0.00008446195,0.000009596184,0.006832016],"genre_scores_gemma":[0.001905228,0.9944147,0.0002815851,0.00001755713,0.0004028798,0.00007594834,0.0005488319,0.00004351435,0.002309682],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9961797,"threshold_uncertainty_score":0.7662134,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04296922347261726,"score_gpt":0.3080519889914634,"score_spread":0.2650827655188461,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}