{"id":"W2087777680","doi":"10.1016/j.ejphar.2015.03.025","title":"The utility of animal models in developing immunosuppressive agents","year":2015,"lang":"en","type":"review","venue":"European Journal of Pharmacology","topic":"Xenotransplantation and immune response","field":"Medicine","cited_by":14,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Montréal; Hôpital Notre-Dame","funders":"","keywords":"Animal model; Medicine; Animal testing; Immunotoxicology; Immune system; Autoimmune disease; Immunology; Disease; Computational biology; Biology; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00279194,0.0002111494,0.00123864,0.0002549761,0.00003923467,0.000008227855,0.0004016354,0.00005856786,0.0001286602],"category_scores_gemma":[0.0001079003,0.0001284465,0.0003304835,0.0002114982,0.0001352054,0.00007836041,0.00006976043,0.0007677492,0.00002293636],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009538054,"about_ca_system_score_gemma":0.001172267,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000002002225,"about_ca_topic_score_gemma":3.130498e-7,"domain_scores_codex":[0.9948007,0.003129683,0.001492913,0.0001218505,0.0002386919,0.0002161706],"domain_scores_gemma":[0.9978384,0.0004034542,0.001216975,0.0001265342,0.0003259723,0.00008864959],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.006991516,0.0003037076,0.000008345375,0.006994572,0.001572311,0.004602906,0.001596241,0.000008094523,0.0006137017,0.00005107158,0.02565919,0.9515983],"study_design_scores_gemma":[0.002177152,0.0004599024,0.0002269269,0.004418128,0.0009618465,0.001760133,0.00004364092,0.00006582619,0.00008517681,0.00000551166,0.9896907,0.0001051175],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001156281,0.9944564,0.00009940237,0.0002408639,0.0006231791,0.0003460785,0.00001112255,0.000003508598,0.003063127],"genre_scores_gemma":[0.005831018,0.9935482,0.000156837,0.0001313163,0.0001346957,0.000001931683,0.000007697467,0.00003592545,0.0001523585],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9640315,"threshold_uncertainty_score":0.5237897,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1637445895242387,"score_gpt":0.4300431248645579,"score_spread":0.2662985353403191,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}