{"id":"W2087799175","doi":"10.1142/s0219720008003801","title":"MODELING OF GLYCEROL-3-PHOSPHATE TRANSPORTER SUGGESTS A POTENTIAL 'TILT' MECHANISM INVOLVED IN ITS FUNCTION","year":2008,"lang":"en","type":"article","venue":"Journal of Bioinformatics and Computational Biology","topic":"Drug Transport and Resistance Mechanisms","field":"Medicine","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Allergy and Infectious Diseases; National Institutes of Health; McGill University","keywords":"Major facilitator superfamily; Transporter; Permease; Transmembrane domain; Periplasmic space; Lactose permease; Membrane transport protein; Transport protein; Protein structure; Biology; Transmembrane protein; ATP-binding cassette transporter; Ligand (biochemistry); Biophysics; Chemistry; Biochemistry; Amino acid; Gene; Receptor","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002170282,0.0001023163,0.0003588092,0.0002431458,0.00003985063,0.000003716381,0.00004868737,0.0001077356,0.00001645152],"category_scores_gemma":[0.000006196585,0.00007662251,0.0001038534,0.0001086115,0.00004540695,0.0001341458,0.000006265445,0.000156664,0.000001099319],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001670779,"about_ca_system_score_gemma":0.0001348927,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004645549,"about_ca_topic_score_gemma":0.00000508516,"domain_scores_codex":[0.9988012,0.00001215818,0.0008107563,0.00006282819,0.0001852727,0.0001277612],"domain_scores_gemma":[0.999312,0.00001723541,0.000267595,0.00004115369,0.0002843796,0.00007758026],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"simulation_or_modeling","study_design_gemma":"simulation_or_modeling","study_design_scores_codex":[0.02533421,0.002897588,0.04666124,0.003534588,0.002382495,0.001332319,0.01749333,0.7303729,0.05203607,0.0894313,0.0001713629,0.0283526],"study_design_scores_gemma":[0.005482654,0.00146653,0.01758908,0.0002300079,0.0001365209,0.000629781,0.0004491383,0.9569428,0.0009450373,0.01592531,0.00004647103,0.0001566681],"study_design_candidate":"simulation_or_modeling","study_design_consensus":"simulation_or_modeling","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7868397,0.0003542844,0.2123156,0.0001745225,0.0001672261,0.00008964637,0.000008246582,0.000004091096,0.00004665528],"genre_scores_gemma":[0.9872498,0.0004266099,0.01204252,0.0001821157,0.00004289148,9.585087e-7,0.00003807796,0.000005712276,0.00001129996],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2265699,"threshold_uncertainty_score":0.3124575,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01585278375623772,"score_gpt":0.2320088704675143,"score_spread":0.2161560867112766,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}