{"id":"W2087823616","doi":"10.1515/hmbci.2010.035","title":"Human type 3 5α-reductase is expressed in peripheral tissues at higher levels than types 1 and 2 and its activity is potently inhibited by finasteride and dutasteride","year":2010,"lang":"en","type":"article","venue":"Hormone Molecular Biology and Clinical Investigation","topic":"Hormonal and reproductive studies","field":"Medicine","cited_by":102,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"Canadian Institutes of Health Research","keywords":"Finasteride; Dihydrotestosterone; Testosterone (patch); Androstenedione; Dutasteride; Internal medicine; Endocrinology; Androgen; Cell culture; Chemistry; Prostate cancer; Prostate; Biology; Medicine; Hormone; Cancer","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000185496,0.0003941641,0.0004551896,0.0003343908,0.0002740907,0.0004671283,0.0001592039,0.0002555838,0.003686809],"category_scores_gemma":[0.0001931909,0.0002548732,0.0006807762,0.0004545158,0.0002247851,0.0001557036,0.000167484,0.0004781475,0.001061447],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003273707,"about_ca_system_score_gemma":0.0002836967,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002558357,"about_ca_topic_score_gemma":0.003513247,"domain_scores_codex":[0.9996372,0.00003456584,0.00002832764,0.0001183057,0.0001031691,0.00007834815],"domain_scores_gemma":[0.9998511,0.00002114129,0.00004262756,0.00002036284,0.00002646548,0.00003822735],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002347825,0.0000209073,0.001932946,0.00008175655,0.00002678122,0.0001127458,0.0000258879,0.00002225371,0.9943091,0.00007827602,0.0001307982,0.003023746],"study_design_scores_gemma":[0.00004480488,0.0004448333,0.08253192,0.00002671444,0.00009356065,0.002993047,0.0001122116,0.0006097024,0.8938935,0.0001379911,0.0190908,0.00002091063],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9614398,0.02116228,0.009296087,0.0003202969,0.0001704647,0.00004038525,0.002345655,0.000326508,0.00489843],"genre_scores_gemma":[0.97925,0.003952277,0.00330602,0.0001758923,0.00004673805,0.00003023379,0.003431738,0.00004732805,0.009759826],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003686809,"threshold_uncertainty_score":0.01233363,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04635666762629268,"score_gpt":0.3623164409857337,"score_spread":0.315959773359441,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}