{"id":"W2087823616","doi":"10.1515/hmbci.2010.035","title":"Human type 3 5α-reductase is expressed in peripheral tissues at higher levels than types 1 and 2 and its activity is potently inhibited by finasteride and dutasteride","year":2010,"lang":"en","type":"article","venue":"Hormone Molecular Biology and Clinical Investigation","topic":"Hormonal and reproductive studies","field":"Medicine","cited_by":102,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"Canadian Institutes of Health Research","keywords":"Finasteride; Dihydrotestosterone; Testosterone (patch); Androstenedione; Dutasteride; Internal medicine; Endocrinology; Androgen; Cell culture; Chemistry; Prostate cancer; Prostate; Biology; Medicine; Hormone; Cancer","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002381587,0.0001724138,0.0003517191,0.00004217344,0.0001160903,0.00001441462,0.00002473778,0.0002427971,0.00001849693],"category_scores_gemma":[0.0001613433,0.0001335693,0.00002467857,0.00007423641,0.0007816386,0.00006836638,0.0001392809,0.0002882108,0.000001985153],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00000686255,"about_ca_system_score_gemma":0.0000148888,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006123635,"about_ca_topic_score_gemma":0.00002433205,"domain_scores_codex":[0.998885,0.0001217353,0.000260479,0.0005111486,0.00006204025,0.0001595655],"domain_scores_gemma":[0.9995275,0.00004278768,0.00008794419,0.0001246031,0.00006499614,0.0001521608],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0002313267,0.00005107509,0.05753782,0.00002641091,0.00006736915,0.00001489846,0.0002696426,1.457062e-8,0.9401026,0.0001016429,0.0002514891,0.001345709],"study_design_scores_gemma":[0.001288586,0.0009396686,0.8081912,0.00003337078,0.00007917492,0.0000333104,0.00003721948,0.00003344934,0.1869077,0.001610056,0.0006678635,0.000178333],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9891803,0.005290861,0.000003221916,0.00512805,0.00006444239,0.0002217376,0.00004364333,0.0000145911,0.00005321576],"genre_scores_gemma":[0.9977172,0.0007057582,0.0001602196,0.0008517856,0.00007724571,0.00000832723,0.00003956934,0.00001159685,0.0004282818],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7531949,"threshold_uncertainty_score":0.5446799,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04635666762629268,"score_gpt":0.3623164409857337,"score_spread":0.315959773359441,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}