{"id":"W2087858817","doi":"10.1016/j.exer.2011.06.015","title":"Elevated membrane attack complex in human choroid with high risk complement factor H genotypes","year":2011,"lang":"en","type":"article","venue":"Experimental Eye Research","topic":"Retinal Diseases and Treatments","field":"Medicine","cited_by":123,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Foundation Fighting Blindness; National Eye Institute; Howard Hughes Medical Institute","keywords":"Genotype; Factor H; Choroid; Allele; Macular degeneration; Complement system; Complement membrane attack complex; Biology; Risk factor; Genetics; Internal medicine; Immunology; Gene; Medicine; Antibody; Retina; Ophthalmology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003449217,0.0005204012,0.0003045758,0.001897014,0.0005859363,0.0004611874,0.0004126758,0.0008483645,0.004501774],"category_scores_gemma":[0.002638262,0.0003507307,0.000252797,0.0007196927,0.0006428733,0.0003759762,0.0005368937,0.0006250347,0.0003317382],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005026198,"about_ca_system_score_gemma":0.0003244114,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.005462633,"about_ca_topic_score_gemma":0.001638078,"domain_scores_codex":[0.9994641,0.0001300767,0.0000612513,0.0001139588,0.0001296314,0.0001010162],"domain_scores_gemma":[0.9986817,0.0004320511,0.0003932569,0.0001350441,0.0001471119,0.0002107429],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.02042117,0.0006716189,0.5669302,0.0001598638,0.0003028655,0.03582906,0.001896714,0.0004328703,0.3599793,0.001795093,0.001119049,0.01046222],"study_design_scores_gemma":[0.0003067623,0.00156992,0.9076036,0.00002613043,0.0002383412,0.04049913,0.001194675,0.001674695,0.04428256,0.001035235,0.001518357,0.00005047914],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9988845,0.0001507245,0.0001562297,0.00004813289,0.000009306013,0.00001156484,0.0001002471,0.000007005648,0.000632284],"genre_scores_gemma":[0.9994166,0.00004076343,0.0001065041,0.00001860125,0.000007430358,0.000007461104,0.00008240723,0.000004400469,0.000315798],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005462633,"threshold_uncertainty_score":0.01505989,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2153664064805919,"score_gpt":0.4532662733164459,"score_spread":0.237899866835854,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}