{"id":"W2087899304","doi":"10.1021/ol3023177","title":"Hydrogen Bonding Directed Intermolecular Cope-Type Hydroamination of Alkenes","year":2012,"lang":"en","type":"article","venue":"Organic Letters","topic":"Catalytic C–H Functionalization Methods","field":"Chemistry","cited_by":36,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"","keywords":"Hydroamination; Chemistry; Intermolecular force; Markovnikov's rule; Regioselectivity; Vicinal; Hydrogen bond; Allylic rearrangement; Reactivity (psychology); Combinatorial chemistry; Catalysis; Organic chemistry; Molecule","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001233408,0.0003255556,0.000167001,0.0001199381,0.0001186063,0.0001438051,0.0002876617,0.0002191128,0.001616116],"category_scores_gemma":[0.0001519443,0.0001554733,0.0001459248,0.00007967735,0.0001775583,0.000291673,0.0003635199,0.0004293742,0.0004296448],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001439167,"about_ca_system_score_gemma":0.0001272035,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001337724,"about_ca_topic_score_gemma":0.0004202877,"domain_scores_codex":[0.9999025,0.000012616,0.000006188751,0.00002072712,0.00002511275,0.00003281285],"domain_scores_gemma":[0.9999141,0.00001703577,0.00002806424,0.00001629308,0.00001008721,0.00001444141],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005618001,0.00003575977,0.0001494646,0.00008650123,0.00001193617,0.0001584511,0.00004206633,0.0005850695,0.9907227,0.001293933,0.0001809374,0.006677034],"study_design_scores_gemma":[0.00001352817,0.0001738941,0.0005497549,0.000003654199,0.000004318648,0.0001520677,0.00001149976,0.0007344147,0.9963367,0.0001273544,0.001885936,0.000006959567],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9768637,0.0007751278,0.01150941,0.00009222607,0.00004733607,0.00004715674,0.000150644,0.0001482247,0.0103663],"genre_scores_gemma":[0.9937381,0.0005076957,0.003486256,0.00003092757,0.00001357533,0.0000256015,0.0001153634,0.00001876722,0.002063707],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001616116,"threshold_uncertainty_score":0.005406439,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01314011736327263,"score_gpt":0.2526811766477302,"score_spread":0.2395410592844575,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}