{"id":"W2087921363","doi":"10.1074/jbc.m908925199","title":"A1 Functions at the Mitochondria to Delay Endothelial Apoptosis in Response to Tumor Necrosis Factor","year":2000,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Cell death mechanisms and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":95,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; St. Paul's Hospital; Vancouver General Hospital","funders":"Medical Research Council; Medical Research Council Canada; Heart and Stroke Foundation of Canada","keywords":"Apoptosis; Tumor necrosis factor alpha; Mitochondrion; Necrosis; Tumor necrosis factor α; Cancer research; Cell biology; Medicine; Chemistry; Biology; Immunology; Internal medicine; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001496909,0.0003185029,0.0001874663,0.0002108346,0.0002642474,0.000339333,0.0002535448,0.0003346516,0.000990935],"category_scores_gemma":[0.0001623254,0.0001024104,0.0001918166,0.0001117694,0.0002131746,0.0002860459,0.000158463,0.0005202199,0.0005075113],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003493713,"about_ca_system_score_gemma":0.0002760173,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002769201,"about_ca_topic_score_gemma":0.0003556662,"domain_scores_codex":[0.9999065,0.00002320598,0.00000941538,0.00001687577,0.00001787772,0.0000260429],"domain_scores_gemma":[0.9998548,0.00002314974,0.00004154684,0.0000187324,0.00001825473,0.00004350319],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002631551,0.0000574138,0.000172111,0.00004510735,0.000006505585,0.00005692329,0.000007379573,0.00008130311,0.9968994,0.0001862961,0.00007649318,0.002147992],"study_design_scores_gemma":[0.00004394317,0.0005745121,0.002952991,0.000008272764,0.00001559833,0.0004079627,0.00001648688,0.000581594,0.9921324,0.0001321238,0.003129457,0.000004703661],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9887567,0.005504411,0.003394381,0.0002974654,0.00006633312,0.00001953688,0.0002233056,0.0001284613,0.001609432],"genre_scores_gemma":[0.9935222,0.002381221,0.001884433,0.00006628592,0.00002334416,0.00002148527,0.0002901851,0.00001192251,0.001798923],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000990935,"threshold_uncertainty_score":0.003314972,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01303370756369615,"score_gpt":0.2421753786886467,"score_spread":0.2291416711249505,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}