{"id":"W2088001012","doi":"10.1021/bi1008479","title":"Leucine-Rich Pentatricopeptide-Repeat Containing Protein Regulates Mitochondrial Transcription","year":2010,"lang":"en","type":"article","venue":"Biochemistry","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":49,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute of Diabetes and Digestive and Kidney Diseases; National Institute of General Medical Sciences","keywords":"Pentatricopeptide repeat; Mitochondrial DNA; DNAJA3; Biology; Mitochondrion; Messenger RNA; Transcription (linguistics); Molecular biology; Gene expression; mitochondrial fusion; Cell biology; Gene; Genetics; RNA editing","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001386936,0.0002678051,0.0002007492,0.00004370669,0.0001428493,0.00005032291,0.0002552255,0.0005027034,0.0004319414],"category_scores_gemma":[0.0002262989,0.0002676479,0.0001577817,0.000117206,0.0001249429,0.000007036587,0.0000623844,0.000321655,0.00005821295],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001458199,"about_ca_system_score_gemma":0.0001242591,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002040211,"about_ca_topic_score_gemma":0.00003198184,"domain_scores_codex":[0.9984626,0.00004733899,0.0003277373,0.0006441419,0.000170526,0.0003476608],"domain_scores_gemma":[0.9989916,0.00001033444,0.0001200607,0.0005860444,0.0001257493,0.000166178],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000401281,0.0000569312,0.0004545333,0.0000266601,0.00002687305,0.000007953166,0.00003116798,0.00000257127,0.992233,0.00005638913,0.006089356,0.0006132827],"study_design_scores_gemma":[0.001228029,0.000222608,0.0001468772,0.00001217332,0.00002447319,0.0001103598,0.00007505964,0.00001180182,0.9640152,0.0000410452,0.03380104,0.0003113735],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9927114,0.0001989096,0.0006894838,0.0001927462,0.001488585,0.0003398678,0.0000272498,0.00006046952,0.004291293],"genre_scores_gemma":[0.9816283,0.00001568709,0.00379253,0.0002066232,0.002704653,0.00009121792,0.0004746619,0.0000408477,0.01104551],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02821784,"threshold_uncertainty_score":0.9999776,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008872973840126717,"score_gpt":0.2342474888362074,"score_spread":0.2253745149960807,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}