{"id":"W2088014351","doi":"10.1369/jhc.5a6899.2006","title":"Epithelial Trafficking of Sonic Hedgehog by Megalin","year":2006,"lang":"en","type":"article","venue":"Journal of Histochemistry & Cytochemistry","topic":"Hedgehog Signaling Pathway Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":37,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval; McGill University","funders":"National Institute of Dental and Craniofacial Research; National Institutes of Health","keywords":"Endocytosis; Endocytic cycle; Cell biology; Endosome; Internalization; Epithelium; Cholangiocyte; Extracellular; Chemistry; Biology; Golgi apparatus; Cell; Intracellular; Biochemistry; Endocrinology; Endoplasmic reticulum","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009645698,0.0002173319,0.0001473962,0.0001728627,0.0001561047,0.0003215981,0.000142952,0.0002138645,0.0007312445],"category_scores_gemma":[0.00009756243,0.00016019,0.0001701065,0.00005863564,0.0002153453,0.0002974008,0.000225677,0.0003499778,0.0002534157],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003197436,"about_ca_system_score_gemma":0.0001705981,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006026358,"about_ca_topic_score_gemma":0.0007952614,"domain_scores_codex":[0.9999284,0.00001221511,0.000005479883,0.00001522818,0.00002310041,0.00001557109],"domain_scores_gemma":[0.9999475,0.0000129131,0.00001271186,0.000007963214,0.000008853353,0.000009987364],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007649615,0.000002992159,0.0002329889,0.00002779608,0.000002999476,0.00008752321,0.00001351261,0.00002602722,0.9983824,0.0001711506,0.00001060509,0.000965458],"study_design_scores_gemma":[0.000004332867,0.00007240181,0.005094631,0.000005869708,0.0000112754,0.0003139067,0.00002574038,0.0003786564,0.9927312,0.00005945758,0.001300316,0.000002274341],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9913032,0.002218347,0.004532482,0.00007429489,0.00001531984,0.000009396748,0.0001110116,0.00005409281,0.001681798],"genre_scores_gemma":[0.9889552,0.001757587,0.004680146,0.00004085552,0.000007565083,0.00001803255,0.0002039391,0.00002771529,0.004308959],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007312445,"threshold_uncertainty_score":0.002446234,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004527779013296637,"score_gpt":0.2175767527202284,"score_spread":0.2130489737069317,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}