{"id":"W2088014351","doi":"10.1369/jhc.5a6899.2006","title":"Epithelial Trafficking of Sonic Hedgehog by Megalin","year":2006,"lang":"en","type":"article","venue":"Journal of Histochemistry & Cytochemistry","topic":"Hedgehog Signaling Pathway Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":37,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval; McGill University","funders":"National Institute of Dental and Craniofacial Research; National Institutes of Health","keywords":"Endocytosis; Endocytic cycle; Cell biology; Endosome; Internalization; Epithelium; Cholangiocyte; Extracellular; Chemistry; Biology; Golgi apparatus; Cell; Intracellular; Biochemistry; Endocrinology; Endoplasmic reticulum","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004815972,0.0004061894,0.0006371254,0.00005518977,0.0001137221,0.00002357406,0.0006499034,0.0003978051,0.00005135342],"category_scores_gemma":[0.0002525521,0.0004103853,0.000531717,0.0001585915,0.000363489,0.00001053167,0.0001209388,0.0003959317,0.000002883942],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001348168,"about_ca_system_score_gemma":0.0004057626,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001380897,"about_ca_topic_score_gemma":0.000001062521,"domain_scores_codex":[0.9972985,0.0000425721,0.001263359,0.000419337,0.0005286906,0.0004475375],"domain_scores_gemma":[0.997505,0.00004516991,0.001223688,0.0004997301,0.0005585207,0.000167889],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002115417,0.0002461445,0.0003653125,0.000197659,0.0001521424,0.00002532558,0.00004014124,0.0002408105,0.964885,0.000003819751,0.03323002,0.0004020618],"study_design_scores_gemma":[0.001210559,0.0001812492,0.00006505391,0.0001374765,0.0001039151,0.0002905755,0.000151824,0.00001281965,0.9728667,0.00004568549,0.02456442,0.0003697993],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9843022,0.01055052,0.001490437,0.0001269267,0.0001688201,0.00009898245,0.0001098997,0.00001635182,0.003135849],"genre_scores_gemma":[0.9953534,0.0001112801,0.001232825,0.00004477407,0.001251315,0.000008415152,0.00008645083,0.00005777907,0.00185379],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01105116,"threshold_uncertainty_score":0.9998348,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004527779013296637,"score_gpt":0.2175767527202284,"score_spread":0.2130489737069317,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}