{"id":"W2088068141","doi":"10.1158/1538-7445.am10-1646","title":"Abstract 1646: Molecular pathways associated with Reolysin and gemcitabine synergy in ras-mutated human HCT116 cells","year":2010,"lang":"en","type":"article","venue":"Cancer Research","topic":"interferon and immune responses","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Oncolytics Biotech (Canada)","funders":"","keywords":"Oncolytic virus; In vivo; Gene; Cell culture; In vitro; Gene expression; Cancer research; Biology; RNA interference; Interferon; Molecular biology; RNA; Virology; Virus; Biochemistry; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009679486,0.000405584,0.0004141181,0.0003925779,0.0002176778,0.0002883427,0.00009878194,0.0002274453,0.001917574],"category_scores_gemma":[0.00009174579,0.0001086701,0.0003653358,0.0005057303,0.0001221809,0.0001846185,0.0001559462,0.0003788917,0.0005448774],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003051918,"about_ca_system_score_gemma":0.0002327467,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006910744,"about_ca_topic_score_gemma":0.0008394988,"domain_scores_codex":[0.9998434,0.0000252658,0.00001412813,0.00003458448,0.00005058037,0.00003205305],"domain_scores_gemma":[0.9999419,0.000009809673,0.00001676498,0.000005783199,0.00001230024,0.00001336873],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002645611,0.00003045508,0.0003152621,0.00008167617,0.000005799652,0.00006271042,0.00001593309,0.00007593014,0.9977919,0.00003385403,0.00009768601,0.001224264],"study_design_scores_gemma":[0.00002646719,0.0005005453,0.03765018,0.00001540335,0.0000301487,0.0002311606,0.00007435619,0.0009413206,0.9564878,0.00007228483,0.003961031,0.000009310088],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9810239,0.004796413,0.003308892,0.0003239081,0.00007951423,0.0001020839,0.006866049,0.0002147421,0.003284414],"genre_scores_gemma":[0.9796311,0.002186384,0.004475722,0.0001772259,0.00001900877,0.0001754752,0.006312998,0.00003195902,0.006990152],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001917574,"threshold_uncertainty_score":0.00641489,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02903385473939606,"score_gpt":0.3275619576715728,"score_spread":0.2985281029321767,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}