{"id":"W2088126954","doi":"10.1182/blood-2009-04-211417","title":"Apolipoprotein-mediated lipid antigen presentation in B cells provides a pathway for innate help by NKT cells","year":2009,"lang":"en","type":"article","venue":"Blood","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":101,"is_retracted":false,"has_abstract":true,"ca_institutions":"Children's & Women's Health Centre of British Columbia; Child and Family Research Institute; University of British Columbia","funders":"","keywords":"Natural killer T cell; Antigen; Antigen presentation; CD1; Biology; Antigen-presenting cell; CD1D; Cell biology; Apolipoprotein B; Cross-presentation; CD40; Immunology; T cell; Cytotoxic T cell; Immune system; Biochemistry; CD8; Cholesterol; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002086904,0.0002738224,0.0002133405,0.0001905257,0.0001599577,0.0005663303,0.0001470657,0.0003281992,0.002413896],"category_scores_gemma":[0.0002234151,0.000103924,0.0002097491,0.00009462643,0.0002233516,0.000325412,0.0004211008,0.0005394287,0.001768575],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002087475,"about_ca_system_score_gemma":0.0002183066,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002364803,"about_ca_topic_score_gemma":0.000196473,"domain_scores_codex":[0.9997876,0.00006629791,0.00001534174,0.00003133401,0.00005022771,0.00004918135],"domain_scores_gemma":[0.9998878,0.00001814267,0.00001293236,0.00002257976,0.00002566303,0.0000329147],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00012947,0.00002460537,0.0003784458,0.00006218783,0.00000453768,0.000147048,0.00001771724,0.00003337572,0.9929338,0.000318937,0.0001263498,0.005823616],"study_design_scores_gemma":[0.0002351358,0.0009543865,0.0103198,0.00004237797,0.00003014906,0.003279463,0.0001299275,0.001247808,0.9632898,0.00149814,0.01895492,0.00001796186],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9553097,0.01287228,0.01619488,0.0007586755,0.00022867,0.0001062131,0.0003020208,0.0004480882,0.01377946],"genre_scores_gemma":[0.9843757,0.002581964,0.008171144,0.0001360087,0.00008532296,0.00004463385,0.0002402294,0.00004204767,0.004322985],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002413896,"threshold_uncertainty_score":0.008075297,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008083865804594028,"score_gpt":0.2203345868213744,"score_spread":0.2122507210167804,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}