{"id":"W2088179337","doi":"10.1021/bi702149b","title":"Structural Characterization of the Cytosolic Domain of Kidney Chloride/Bicarbonate Anion Exchanger 1 (kAE1)","year":2008,"lang":"en","type":"article","venue":"Biochemistry","topic":"Erythrocyte Function and Pathophysiology","field":"Medicine","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canada Research Chairs; University of Toronto","funders":"","keywords":"Chemistry; Circular dichroism; Bicarbonate; Cytosol; Biophysics; Biochemistry; Protein structure; Tryptophan; Osmolyte; Amino acid; Crystallography; Biology; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00003625967,0.00009369695,0.0001935774,0.00002126701,0.00004012771,8.706426e-7,0.00007037483,0.0001194286,0.0001636238],"category_scores_gemma":[0.00007022897,0.00006551528,0.00009205059,0.0001425001,0.0001599485,0.00001784938,0.00003589744,0.00009345175,0.000002679938],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002171393,"about_ca_system_score_gemma":0.0001350351,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000008484996,"about_ca_topic_score_gemma":9.995603e-8,"domain_scores_codex":[0.9993942,0.00001759426,0.0002017381,0.0001406818,0.0001418667,0.0001039205],"domain_scores_gemma":[0.9993739,0.000009351951,0.0001656138,0.0002798324,0.0000838721,0.00008742678],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001900517,0.00002595954,0.005717482,0.0001654846,0.00002130906,0.000001996442,0.0001889324,1.408846e-7,0.9934296,0.000009024437,0.0002030372,0.00004700314],"study_design_scores_gemma":[0.0005920538,0.00005265097,0.08427441,0.00006789402,0.00002064048,0.00008295386,0.0000281935,0.00003176562,0.9143358,0.00001690762,0.0004401247,0.0000566075],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9983783,0.00002946685,0.000007896822,0.0003733278,0.0002631984,0.00010855,0.00003580846,0.0000178373,0.000785614],"genre_scores_gemma":[0.9980733,0.00005859578,0.00004429662,0.0004693114,0.0002780693,0.000005142475,0.0001396044,0.00001031033,0.0009213556],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07909378,"threshold_uncertainty_score":0.2671635,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01573608958418349,"score_gpt":0.2264897374642335,"score_spread":0.21075364788005,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}