{"id":"W2088234095","doi":"10.1016/j.molimm.2008.08.003","title":"Mutational analyses reveal that the staphylococcal immune evasion molecule Sbi and complement receptor 2 share overlapping contact residues on C3d: Implications for the controversy regarding the CR2/C3d co-crystal structure","year":2008,"lang":"en","type":"article","venue":"Molecular Immunology","topic":"Peptidase Inhibition and Analysis","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Evasion (ethics); Complement (music); Immune system; Complement receptor; Microbiology; Molecule; Chemistry; Biology; Immunology; Computational biology; Complement system; Genetics; Gene; Organic chemistry; Mutant","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001310569,0.0002643802,0.0002125687,0.0001386521,0.0002425992,0.0003324071,0.0002616881,0.0003542122,0.001308901],"category_scores_gemma":[0.0002686921,0.0000827182,0.0002264108,0.000172515,0.0002450256,0.0001659596,0.0002093074,0.0005848403,0.0003409625],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005428274,"about_ca_system_score_gemma":0.0003448819,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001951181,"about_ca_topic_score_gemma":0.00161009,"domain_scores_codex":[0.9999253,0.00001139537,0.000005455614,0.00001477311,0.00002842715,0.00001468693],"domain_scores_gemma":[0.9999026,0.00003588629,0.00002328318,0.000009030535,0.00001053678,0.00001867929],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007546386,0.00009856381,0.005955237,0.00006524201,0.00003864816,0.0009863683,0.0001198446,0.0008644651,0.980639,0.003613665,0.0006966137,0.006167569],"study_design_scores_gemma":[0.0001792408,0.0002922447,0.03815328,0.00002417961,0.0001048721,0.005296651,0.0002655245,0.01549781,0.9313421,0.001599342,0.007219349,0.00002545302],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9944912,0.0004933273,0.002484221,0.00027743,0.00002459142,0.0000112889,0.0002671364,0.0000290481,0.001921776],"genre_scores_gemma":[0.9970472,0.0001390143,0.001950428,0.00008981827,0.000005504602,0.000006243042,0.0003216617,0.000005517053,0.0004346435],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001951181,"threshold_uncertainty_score":0.004378676,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04840419424571932,"score_gpt":0.3360103170686699,"score_spread":0.2876061228229505,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}