{"id":"W2088250437","doi":"10.1159/000323790","title":"Dual, Constrictor-to-Dilator, Response of the Mouse Ductus Arteriosus to the Microsomal Prostaglandin E Synthase-1 Inhibitor, 2-(6-Chloro-1H-phenanthro[9,10<i>d</i>]imidazole- 2-yl)isophthalonitrile","year":2011,"lang":"en","type":"article","venue":"Neonatology","topic":"Cardiovascular Conditions and Treatments","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"Merck Canada Inc. (Canada)","funders":"","keywords":"Ductus arteriosus; In vivo; Prostaglandin; Dilator; Internal medicine; Prostaglandin E; Endocrinology; Ex vivo; Nitric oxide synthase; Chemistry; Medicine; Nitric oxide; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000523587,0.0004902968,0.0009239019,0.0003614652,0.0004302183,0.00003002853,0.0003720921,0.0003234871,0.000789601],"category_scores_gemma":[0.0004856356,0.0003106568,0.0006143862,0.0007524285,0.0006703796,0.00008306088,0.0002838171,0.0002791332,0.0004291202],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001945053,"about_ca_system_score_gemma":0.0004294347,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006865167,"about_ca_topic_score_gemma":0.0001299597,"domain_scores_codex":[0.9966831,0.000490436,0.0007214018,0.0007254891,0.0005560526,0.0008234948],"domain_scores_gemma":[0.9970127,0.000365639,0.000238037,0.001657945,0.0003483861,0.0003773058],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.02248581,0.003275135,0.0603478,0.0002317399,0.004611987,0.009268454,0.008346275,0.00002748803,0.8207402,0.004467476,0.06281404,0.003383555],"study_design_scores_gemma":[0.01169694,0.003076969,0.2597071,0.0003027182,0.001664172,0.02328055,0.0005416888,0.00001879159,0.4622967,0.0001425989,0.2362068,0.001064966],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9919799,0.001353119,0.00005675957,0.001736047,0.0009095151,0.002230043,0.0005086156,0.0001000478,0.001125928],"genre_scores_gemma":[0.997014,0.00004668166,0.0004496446,0.0004651397,0.000177604,0.0003468224,0.00005124486,0.00007712257,0.001371703],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3584435,"threshold_uncertainty_score":0.9999346,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01690379265355173,"score_gpt":0.240692306160456,"score_spread":0.2237885135069042,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}