{"id":"W2088250437","doi":"10.1159/000323790","title":"Dual, Constrictor-to-Dilator, Response of the Mouse Ductus Arteriosus to the Microsomal Prostaglandin E Synthase-1 Inhibitor, 2-(6-Chloro-1H-phenanthro[9,10<i>d</i>]imidazole- 2-yl)isophthalonitrile","year":2011,"lang":"en","type":"article","venue":"Neonatology","topic":"Cardiovascular Conditions and Treatments","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"Merck Canada Inc. (Canada)","funders":"","keywords":"Ductus arteriosus; In vivo; Prostaglandin; Dilator; Internal medicine; Prostaglandin E; Endocrinology; Ex vivo; Nitric oxide synthase; Chemistry; Medicine; Nitric oxide; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005000929,0.0006055197,0.0006276311,0.0004023788,0.0002000743,0.0002536137,0.0003806273,0.0006482954,0.002221954],"category_scores_gemma":[0.0002828899,0.000274344,0.0005085373,0.0002111311,0.0005509799,0.0004906558,0.000325184,0.002047648,0.0005579322],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003268596,"about_ca_system_score_gemma":0.0003043857,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003073508,"about_ca_topic_score_gemma":0.0007444769,"domain_scores_codex":[0.9995011,0.00008441159,0.0000478338,0.0001234112,0.0001066631,0.0001366847],"domain_scores_gemma":[0.9992901,0.0001434992,0.0001803222,0.00007689976,0.00004230848,0.0002667857],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007217695,0.0001486153,0.0001317805,0.00005201091,0.0000070536,0.00008217654,0.00002992437,0.0000339792,0.9977353,0.00004280202,0.00007451895,0.0009402214],"study_design_scores_gemma":[0.00009352018,0.004660056,0.005304543,0.000011762,0.00002750881,0.000237225,0.00004250542,0.000498608,0.9881715,0.00003275871,0.0009133962,0.000006522049],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9932694,0.001790344,0.001897798,0.0002589824,0.0001737315,0.0000841225,0.0005787731,0.0001496281,0.001797154],"genre_scores_gemma":[0.9832566,0.002175302,0.005631054,0.0003561484,0.0002581027,0.0002916818,0.001072395,0.00007012369,0.006888566],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002221954,"threshold_uncertainty_score":0.007433116,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01690379265355173,"score_gpt":0.240692306160456,"score_spread":0.2237885135069042,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}