{"id":"W2088254327","doi":"10.1007/s11302-011-9259-2","title":"Imaging exocytosis of ATP-containing vesicles with TIRF microscopy in lung epithelial A549 cells","year":2011,"lang":"en","type":"article","venue":"Purinergic Signalling","topic":"Adenosine and Purinergic Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":58,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Montréal","funders":"National Cancer Institute; National Heart, Lung, and Blood Institute; Canadian Institutes of Health Research; National Institutes of Health","keywords":"Exocytosis; Cell biology; Vesicle; Nocodazole; Cytochalasin D; Microvesicle; Biology; Secretion; Biophysics; Secretory Vesicle; Vesicular transport protein; Brefeldin A; Vesicle fusion; Cytochalasin B; Chemistry; Biochemistry; Golgi apparatus; Microvesicles; Cytoskeleton; Endoplasmic reticulum; Synaptic vesicle; Cell","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000291916,0.0002908511,0.000327062,0.0001542519,0.00007129344,0.00002055199,0.0003128269,0.000103508,0.0001049807],"category_scores_gemma":[0.00001812628,0.000264971,0.0001102939,0.0002148054,0.0001049649,0.00001636736,0.0001175651,0.000160909,0.0000048067],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000220709,"about_ca_system_score_gemma":0.00008723069,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003264146,"about_ca_topic_score_gemma":0.00001047507,"domain_scores_codex":[0.9983178,0.00006481312,0.0004758029,0.0004915781,0.0001873801,0.0004626263],"domain_scores_gemma":[0.999259,0.00003492155,0.0002226589,0.0002897138,0.00009777889,0.00009594436],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000501777,0.000100238,0.02513941,0.00006139392,0.00006633438,0.00005897212,0.0008618212,0.001782714,0.970886,0.00005068825,0.0001395357,0.0003511241],"study_design_scores_gemma":[0.001140139,0.0002365637,0.001012617,0.0001644796,0.00004865889,0.00002437507,0.0004554999,0.0008708922,0.9951836,0.00004198801,0.0004615601,0.0003596146],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9892021,0.003718745,0.005370447,0.00002487414,0.00009189761,0.0001765641,0.000009780128,0.00002295058,0.001382634],"genre_scores_gemma":[0.9936919,0.0001512436,0.005533831,0.000115849,0.0002647024,0.00002612921,0.00002443438,0.00005849777,0.0001334139],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02429762,"threshold_uncertainty_score":0.9999803,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01188769597749838,"score_gpt":0.2275596779674286,"score_spread":0.2156719819899302,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}