{"id":"W2088348859","doi":"10.1016/j.bpj.2013.11.2992","title":"Cytosolic Activation Dynamics in the KV Channel Probed by a Fluorescent Unnatural Amino Acid","year":2014,"lang":"en","type":"article","venue":"Biophysical Journal","topic":"Ion channel regulation and function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Montréal","funders":"","keywords":"Shaker; Biophysics; Amino acid; Chemistry; Fluorescence; Fluorophore; Cytosol; Potassium channel; Voltage clamp; Ion channel; Membrane potential; Biochemistry; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001502337,0.0001403722,0.0001418169,0.00005914895,0.0002281779,0.0003846953,0.0003074111,0.0003210158,0.001265729],"category_scores_gemma":[0.0002746337,0.000117784,0.0001215677,0.00009002069,0.000426257,0.0005275978,0.0001688172,0.0006832282,0.0001876208],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004904778,"about_ca_system_score_gemma":0.0002333229,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009406839,"about_ca_topic_score_gemma":0.0008568459,"domain_scores_codex":[0.9999355,0.000008063403,0.000003318914,0.00001858107,0.00001413624,0.00002027338],"domain_scores_gemma":[0.9998573,0.00005407546,0.00003045692,0.00001437425,0.00001430669,0.00002936971],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004436185,0.00002419954,0.0001517405,0.00002212922,0.000003328731,0.0001045508,0.00005659632,0.0002523248,0.9970331,0.0008043806,0.0000495817,0.001054512],"study_design_scores_gemma":[0.00005079085,0.0001425631,0.002037705,0.000005530058,0.000009919535,0.0002488923,0.00007161988,0.00867206,0.9873192,0.0003720567,0.001055181,0.00001440763],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9961832,0.0001520188,0.002715644,0.00009648479,0.00001386266,0.000003742556,0.00004705039,0.00002999722,0.0007578333],"genre_scores_gemma":[0.9983247,0.0001007887,0.0008679854,0.00002612524,0.000004318353,0.000003975336,0.00005850161,0.0000159775,0.0005976161],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001265729,"threshold_uncertainty_score":0.004234314,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007761442349051417,"score_gpt":0.2268065087664501,"score_spread":0.2190450664173987,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}