{"id":"W2088351141","doi":"10.1002/pro.2049","title":"Inositol phosphate‐induced stabilization of inositol 1,3,4,5,6‐pentakisphosphate 2‐kinase and its role in substrate specificity","year":2012,"lang":"en","type":"article","venue":"Protein Science","topic":"Phytase and its Applications","field":"Agricultural and Biological Sciences","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Canadian Institutes of Health Research; University of East Anglia; McGill University","keywords":"Inositol; Kinase; Inositol phosphate; Phosphorylation; Chemistry; Substrate (aquarium); Stereochemistry; Phosphate; Biophysics; Biochemistry; Receptor; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005138215,0.0001051529,0.0001287666,0.00002659852,0.0001909969,0.0000498353,0.000282322,0.0000447516,0.00007299303],"category_scores_gemma":[0.00005315475,0.00005003295,0.00001930487,0.001150955,0.0001334458,0.0007838079,0.00009794603,0.00007960389,0.0000155706],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003305013,"about_ca_system_score_gemma":0.00002245038,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003293233,"about_ca_topic_score_gemma":0.0001307774,"domain_scores_codex":[0.9988208,0.00003366166,0.0002370337,0.00027913,0.0002770716,0.0003522703],"domain_scores_gemma":[0.9995224,0.00003245809,0.0001246064,0.00007321097,0.00009714143,0.000150184],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001037096,0.0001355264,0.03693191,0.000006074208,6.343698e-7,2.258674e-7,0.000176686,7.942615e-7,0.951571,0.003425157,0.000002490271,0.007739158],"study_design_scores_gemma":[0.00006003027,0.00004312603,0.3070179,0.00001653644,0.000001571243,7.500974e-7,0.0001610085,0.0001260087,0.6919995,0.0002888227,0.0002012664,0.00008350988],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9980111,0.0007310846,0.000002370126,0.0001945799,0.00003830498,0.0006350004,0.00001822434,0.00001963261,0.0003497144],"genre_scores_gemma":[0.9997144,0.00003673177,0.00009132211,0.00002721886,0.00004356962,0.00006639565,0.00000608292,7.463843e-7,0.00001347133],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.270086,"threshold_uncertainty_score":0.2040285,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0272269736288858,"score_gpt":0.2502382345606597,"score_spread":0.2230112609317739,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}