{"id":"W2088390557","doi":"10.1016/j.biomaterials.2011.11.079","title":"Supramolecular assemblies in functional siRNA delivery: Where do we stand?","year":2011,"lang":"en","type":"review","venue":"Biomaterials","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":131,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research","keywords":"Small interfering RNA; Gene silencing; RNA interference; Site of action; Nanotechnology; Supramolecular chemistry; Computational biology; RNA; Materials science; Biology; Chemistry; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00127119,0.001119785,0.00178815,0.0009766282,0.0004144544,0.001467334,0.001340903,0.002094025,0.001451939],"category_scores_gemma":[0.000723537,0.0004783729,0.0003447618,0.00182772,0.001211073,0.002229257,0.0009130955,0.002302464,0.001827042],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001021549,"about_ca_system_score_gemma":0.0009700412,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008597423,"about_ca_topic_score_gemma":0.00201513,"domain_scores_codex":[0.9998167,0.00004004909,0.00002106952,0.00003498631,0.00006113732,0.00002602477],"domain_scores_gemma":[0.9997025,0.0001549402,0.00004112015,0.00001060019,0.00006058564,0.00003023249],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001195798,0.0001172411,0.0001164007,0.0129238,0.00008171028,0.0002546016,0.00008304548,0.0008318952,0.01068485,0.01606843,0.039285,0.9194333],"study_design_scores_gemma":[0.00003423123,0.0001183619,0.0003191549,0.002097205,0.0000876209,0.0007731747,0.00007275183,0.0003329931,0.003892889,0.005349272,0.9868835,0.00003890717],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001279187,0.99818,0.0004335741,0.0003571866,0.0002754019,0.000003017613,0.000006322537,0.000007558648,0.0006091123],"genre_scores_gemma":[0.0014151,0.9966259,0.0004654902,0.0003567162,0.0002522044,0.00001136159,0.00001513402,0.000002482155,0.0008556516],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002094025,"threshold_uncertainty_score":0.007411897,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0588388678860115,"score_gpt":0.3032262639703799,"score_spread":0.2443873960843684,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}