{"id":"W2088390603","doi":"10.1111/j.1399-0004.2008.01081.x","title":"Promoting ectopic pancreatic fates: pancreas development and future diabetes therapies","year":2008,"lang":"en","type":"review","venue":"Clinical Genetics","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Centre Hospitalier de l’Université de Montréal; Université de Montréal; Montreal Clinical Research Institute","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institutes of Health","keywords":"PDX1; Biology; Zebrafish; Pancreas; Transdifferentiation; Progenitor cell; Enteroendocrine cell; PAX4; Stem cell; Cell biology; Foregut; Beta cell; Cellular differentiation; Cell type; Embryonic stem cell; Endocrine system; Endocrinology; Cell; Genetics; Hormone; Diabetes mellitus; Gene; Homeobox; Anatomy; Islet; Transcription factor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003940355,0.0005970719,0.003042274,0.0001246252,0.0001516578,0.00004132307,0.0001518795,0.0006963566,0.00009903398],"category_scores_gemma":[0.0005248878,0.0004116101,0.000492761,0.0002435366,0.0002658551,0.00002175749,0.0001115294,0.0006455241,0.0001166492],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005394519,"about_ca_system_score_gemma":0.0006177902,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":6.471009e-7,"about_ca_topic_score_gemma":3.288298e-7,"domain_scores_codex":[0.9966645,0.0002861365,0.001582331,0.000688917,0.0003028293,0.0004752488],"domain_scores_gemma":[0.9973205,0.001126058,0.0004553823,0.0005602861,0.0001104721,0.0004272728],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000005084188,0.0001436778,0.01358497,0.007766014,0.0007074843,0.00001807893,0.0002112571,7.447656e-9,6.893098e-7,0.000007097023,0.0003806286,0.977175],"study_design_scores_gemma":[0.0006753607,0.000329317,0.004593011,0.006975552,0.001426271,0.00005688536,0.00004445897,0.00001801963,0.00001024584,0.0000213902,0.9854437,0.0004058551],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.03793801,0.9596629,0.000003491165,0.0001021979,0.0005421193,0.0009685685,0.000007866166,0.000113929,0.0006609209],"genre_scores_gemma":[0.00006102524,0.9906535,0.005538638,0.0004838589,0.002116201,0.0001277878,0.0001302171,0.00008881568,0.0007999544],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.985063,"threshold_uncertainty_score":0.9998336,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09218929873205035,"score_gpt":0.3686584284222412,"score_spread":0.2764691296901909,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}