{"id":"W2088390603","doi":"10.1111/j.1399-0004.2008.01081.x","title":"Promoting ectopic pancreatic fates: pancreas development and future diabetes therapies","year":2008,"lang":"en","type":"review","venue":"Clinical Genetics","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Centre Hospitalier de l’Université de Montréal; Université de Montréal; Montreal Clinical Research Institute","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institutes of Health","keywords":"PDX1; Biology; Zebrafish; Pancreas; Transdifferentiation; Progenitor cell; Enteroendocrine cell; PAX4; Stem cell; Cell biology; Foregut; Beta cell; Cellular differentiation; Cell type; Embryonic stem cell; Endocrine system; Endocrinology; Cell; Genetics; Hormone; Diabetes mellitus; Gene; Homeobox; Anatomy; Islet; Transcription factor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004969929,0.0007886423,0.00137301,0.001734401,0.0002477959,0.000802872,0.0009369347,0.001358534,0.00325121],"category_scores_gemma":[0.0004093083,0.0002460564,0.0003621422,0.001459553,0.0005511038,0.001544642,0.0005400116,0.001610698,0.002544252],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005590604,"about_ca_system_score_gemma":0.0005458193,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005044833,"about_ca_topic_score_gemma":0.001205399,"domain_scores_codex":[0.9998399,0.00002996903,0.00002191377,0.00002505191,0.00006741546,0.00001564152],"domain_scores_gemma":[0.9998153,0.00008007916,0.0000255532,0.000008239456,0.00004457038,0.00002631876],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00007239873,0.0001027544,0.0001425336,0.006293708,0.00004851928,0.0003561045,0.00004873305,0.0004300786,0.004015041,0.003354265,0.01798517,0.9671507],"study_design_scores_gemma":[0.00003734384,0.0001326609,0.0009954635,0.002049865,0.00006179028,0.002848948,0.00007757766,0.0001449961,0.001137448,0.002421658,0.9900709,0.00002153399],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002117905,0.9974419,0.0003251785,0.000331654,0.0002054336,0.000004380798,0.00000911942,0.00001632371,0.001454176],"genre_scores_gemma":[0.0007000107,0.9976795,0.000390148,0.0001895492,0.0001248718,0.000007736598,0.00001961161,0.000001962718,0.0008866396],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.00325121,"threshold_uncertainty_score":0.01087642,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09218929873205035,"score_gpt":0.3686584284222412,"score_spread":0.2764691296901909,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}