{"id":"W2088396338","doi":"10.1387/ijdb.052102nb","title":"A hypothesis linking low folate intake to neural tube defects due to failure of post-translation methylations of the cytoskeleton","year":2006,"lang":"en","type":"review","venue":"The International Journal of Developmental Biology","topic":"Folate and B Vitamins Research","field":"Medicine","cited_by":35,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"","keywords":"Neural tube; Biology; Cytoskeleton; Methylation; Cell biology; Biochemistry; Neural tube defect; Folic acid; Cell; Internal medicine; DNA; Embryo","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006801349,0.0002336703,0.0009211015,0.0006604145,0.00005757544,0.00001699693,0.0008554428,0.000196682,0.00005352397],"category_scores_gemma":[0.0003788781,0.0001230188,0.0005485463,0.0004815809,0.00009179537,0.00005782888,0.0002146243,0.0005087791,0.00001614537],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002703241,"about_ca_system_score_gemma":0.0007320491,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007619034,"about_ca_topic_score_gemma":0.0001535868,"domain_scores_codex":[0.9976403,0.000246645,0.001165625,0.0001750523,0.0005683686,0.000204001],"domain_scores_gemma":[0.9977067,0.0006642596,0.000677296,0.0001629098,0.0007064037,0.00008250754],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002772048,0.0001442068,0.0006611884,0.0007797919,0.001440242,0.00004098325,0.0005373226,0.00002310438,0.03650752,0.0001051815,0.0002275378,0.9592557],"study_design_scores_gemma":[0.003995446,0.004230315,0.02307005,0.04096868,0.002959839,0.01115957,0.0005982965,0.00005234665,0.06619129,0.001323951,0.8441873,0.001262922],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.6309105,0.3569185,0.0004258698,0.006855827,0.001507109,0.002325161,0.0003166866,0.00001565079,0.0007246866],"genre_scores_gemma":[0.773851,0.2095362,0.0136665,0.001150971,0.0009837648,0.00005333893,0.0002693135,0.0001146806,0.0003742765],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.9579928,"threshold_uncertainty_score":0.5016562,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05201979273046552,"score_gpt":0.3469866259207394,"score_spread":0.2949668331902738,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}