{"id":"W2088410504","doi":"10.1002/adma.200501043","title":"Biofunctionalized pH‐Responsive Microgels for Cancer Cell Targeting: Rational Design","year":2005,"lang":"en","type":"article","venue":"Advanced Materials","topic":"Nanoparticle-Based Drug Delivery","field":"Materials Science","cited_by":228,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"HeLa; Endocytosis; Materials science; Doxorubicin; Rational design; Drug delivery; Cancer cell; Cytotoxicity; Intracellular; Receptor-mediated endocytosis; Biophysics; Nanotechnology; Targeted drug delivery; Cell; Cell biology; Cancer; Chemistry; Biochemistry; Biology; In vitro; Chemotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003831902,0.0005895891,0.0002989795,0.0003138004,0.0001801279,0.000443299,0.000371757,0.0004679035,0.0005692223],"category_scores_gemma":[0.0002995889,0.0002830747,0.000274168,0.0001645585,0.0002887044,0.0004104923,0.0001509683,0.0004601098,0.0003923179],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007158025,"about_ca_system_score_gemma":0.0004928426,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006163277,"about_ca_topic_score_gemma":0.001250908,"domain_scores_codex":[0.9998829,0.00001742185,0.00001104742,0.00002479428,0.00004067242,0.00002312715],"domain_scores_gemma":[0.9999301,0.00001657055,0.00002208544,0.000006381034,0.00001260298,0.00001226732],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009108245,0.00006661809,0.00008241163,0.0002108515,0.0000136559,0.0001709769,0.00003717188,0.00635891,0.9783891,0.001496427,0.0001336904,0.01294908],"study_design_scores_gemma":[0.00007969976,0.0003328187,0.0002281132,0.00001775986,0.00002484511,0.0001599324,0.00001314362,0.00839067,0.980152,0.0003075991,0.01027094,0.00002253375],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7622931,0.01887748,0.2093696,0.0009310289,0.0002599494,0.001102073,0.0005196017,0.001221382,0.00542573],"genre_scores_gemma":[0.8146615,0.01042659,0.1689245,0.0002423537,0.00004400614,0.0005341021,0.0004113668,0.0001096809,0.004645773],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007158025,"threshold_uncertainty_score":0.005193591,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01882782271334766,"score_gpt":0.2721417029293641,"score_spread":0.2533138802160165,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}