{"id":"W2088454721","doi":"10.1080/03630260802625659","title":"Hb North York [β117(G19)His→Asp]: A New β Chain Hemoglobin Variant","year":2009,"lang":"en","type":"article","venue":"Hemoglobin","topic":"Hemoglobinopathies and Related Disorders","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University; Hamilton Health Sciences; Hamilton Regional Laboratory Medicine Program","funders":"","keywords":"Missense mutation; Hemoglobin; Genetics; Globin; Hemoglobin variants; Mutation; Amino acid substitution; Gene; Biology; Molecular biology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0003640749,0.0007509743,0.001047277,0.0003383893,0.0003195531,0.00009662806,0.0004412491,0.000613143,0.001113067],"category_scores_gemma":[0.0002041131,0.0006487313,0.0005016994,0.001421949,0.000155028,0.0001807403,0.0001039022,0.0009925148,0.001290806],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003552703,"about_ca_system_score_gemma":0.0007519755,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004983213,"about_ca_topic_score_gemma":0.00009583227,"domain_scores_codex":[0.9956512,0.0001073582,0.0009617048,0.001044564,0.0008386941,0.001396446],"domain_scores_gemma":[0.9971372,0.00006754919,0.0002509954,0.001202847,0.0001423558,0.001199032],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.002299522,0.003403566,0.01324218,0.0003924875,0.0006966629,0.005531555,0.004671305,0.0004179296,0.01238557,0.009814246,0.6643672,0.2827778],"study_design_scores_gemma":[0.02884367,0.00500153,0.08431391,0.001527487,0.001311074,0.006406647,0.002150014,0.004020834,0.006455008,0.004928459,0.8512211,0.003820263],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8092502,0.01021757,0.00271233,0.04244176,0.002130873,0.003559017,0.00009333953,0.001925843,0.1276691],"genre_scores_gemma":[0.957249,0.0006090605,0.004761519,0.01364265,0.0009624069,0.00002536351,0.0002163163,0.0001226383,0.02241098],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2789575,"threshold_uncertainty_score":0.9998,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01250243963666057,"score_gpt":0.2349512211267272,"score_spread":0.2224487814900667,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}