{"id":"W2088503826","doi":"10.1242/jcs.036905","title":"Identification of GW182 and its novel isoform TNGW1 as translational repressors in Ago2-mediated silencing","year":2008,"lang":"en","type":"article","venue":"Journal of Cell Science","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":63,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"National Institute of Allergy and Infectious Diseases; National Institutes of Health; University of Alberta; National Institute of Dental and Craniofacial Research; Fondation pour la Recherche Médicale; Arthritis Society; Canadian Institutes of Health Research; Andrew J. Semesco Foundation; Friedrich Miescher Institute for Biomedical Research","keywords":"Biology; Gene silencing; Argonaute; Repressor; RasiRNA; RNA-induced silencing complex; P-bodies; Trans-acting siRNA; Small interfering RNA; Messenger RNA; RNA; Genetics; Cell biology; Molecular biology; Gene expression; Gene; Translation (biology)","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001140186,0.000241593,0.0001867395,0.0001574936,0.000120623,0.0002045237,0.0001558506,0.000187485,0.0004247473],"category_scores_gemma":[0.00007031795,0.0001143837,0.0002111531,0.0001263334,0.0001767731,0.0001813965,0.0002169443,0.0002500947,0.0002415393],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002137155,"about_ca_system_score_gemma":0.0001250601,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002130535,"about_ca_topic_score_gemma":0.0003361305,"domain_scores_codex":[0.999933,0.00000749139,0.000006174402,0.00002677512,0.0000127712,0.00001377273],"domain_scores_gemma":[0.9999491,0.000004946111,0.00001670646,0.000006125779,0.000004623531,0.00001850494],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004488621,0.000003072325,0.0002123199,0.00001090738,0.000001790189,0.00004113737,0.000006621019,0.00001564388,0.9989642,0.00006447748,0.00001069841,0.0006243332],"study_design_scores_gemma":[0.00000961248,0.000110487,0.00906179,0.000003218494,0.00001474541,0.000666019,0.00001781956,0.0008522056,0.985637,0.00007029546,0.00355146,0.000005349917],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9929288,0.001417343,0.00461513,0.00005851852,0.00001479055,0.00001713572,0.0001977744,0.0000629863,0.0006876422],"genre_scores_gemma":[0.9916152,0.0006787395,0.004334401,0.00003141712,0.000007861008,0.000026545,0.0009860465,0.00003163425,0.002287907],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0004247473,"threshold_uncertainty_score":0.001550615,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0165670438825834,"score_gpt":0.2817762109683869,"score_spread":0.2652091670858035,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}