{"id":"W2088522077","doi":"10.1210/en.2004-1540","title":"Endogenous Estrogens Inhibit Mouse Fetal Leydig Cell Development via Estrogen Receptor α","year":2005,"lang":"en","type":"article","venue":"Endocrinology","topic":"Estrogen and related hormone effects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":120,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Institute of Genetics; National Institutes of Health; Institut National de la Santé et de la Recherche Médicale","keywords":"Internal medicine; Endocrinology; Fetus; Leydig cell; Biology; Testosterone (patch); Estrogen; Estrogen receptor; Cholesterol side-chain cleavage enzyme; Diethylstilbestrol; Endogeny; Hormone; Medicine; Pregnancy; Luteinizing hormone; Metabolism; Cytochrome P450","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00008390984,0.0003728732,0.0002858076,0.0001017884,0.0002068621,0.00002063063,0.0003313499,0.0003285827,0.0001220771],"category_scores_gemma":[0.00002352812,0.0003636006,0.0001770208,0.0001000178,0.0001430395,0.000007737563,0.0002596862,0.0003172827,0.001144493],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007055259,"about_ca_system_score_gemma":0.000179691,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001454059,"about_ca_topic_score_gemma":0.0000103643,"domain_scores_codex":[0.9977751,0.0001082919,0.0003933588,0.0006321802,0.0001627548,0.0009283509],"domain_scores_gemma":[0.9991015,0.00001681159,0.000124981,0.0004682835,0.00006364455,0.0002247909],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001025899,0.0002486892,0.001169665,0.00001159701,0.0001613735,0.00005065674,0.0001126452,0.0001171309,0.9774193,0.00007802506,0.001381049,0.01914735],"study_design_scores_gemma":[0.0009717349,0.0003410292,0.00003313345,0.000002910179,0.00002582816,0.0004791944,0.000030984,0.00001436238,0.8230616,0.000004409965,0.1747104,0.0003243614],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9900693,0.004487538,0.000525952,0.0001817101,0.0002194978,0.0003386724,0.00001400581,0.00009603508,0.004067258],"genre_scores_gemma":[0.9874984,0.000358228,0.007789899,0.0002836887,0.0005019983,0.00007917488,0.0003077725,0.00007211226,0.003108729],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1733294,"threshold_uncertainty_score":0.9998816,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009406252025803705,"score_gpt":0.2118695784844546,"score_spread":0.2024633264586509,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}