{"id":"W2088568685","doi":"10.4161/15384101.2014.948787","title":"PARP inhibitors target ATM+p53-defective gastric cancer","year":2014,"lang":"en","type":"letter","venue":"Cell Cycle","topic":"PARP inhibition in cancer therapy","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"DNA damage; Cancer research; Carcinogenesis; Genome instability; DNA repair; Synthetic lethality; Poly ADP ribose polymerase; Homologous recombination; Biology; Cancer; Cell cycle checkpoint; Cell cycle; DNA; Genetics","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008207696,0.0003310731,0.0002932993,0.0002489041,0.0001394584,0.0003800775,0.0002821449,0.0002649884,0.003853232],"category_scores_gemma":[0.00006352062,0.0001196177,0.0002513305,0.0002783806,0.00009403841,0.0001795126,0.0001569343,0.0005595941,0.001360004],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003947389,"about_ca_system_score_gemma":0.0001387234,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005427255,"about_ca_topic_score_gemma":0.001479758,"domain_scores_codex":[0.9999659,0.000003205929,0.000002339284,0.000005759582,0.00001044395,0.00001230281],"domain_scores_gemma":[0.9999795,0.000002246829,0.000005730087,0.000002316746,0.000003648536,0.000006524646],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.003281036,0.0008533175,0.004599457,0.001469106,0.000223328,0.001946381,0.00006158123,0.001867113,0.5973607,0.001756941,0.0258585,0.3607225],"study_design_scores_gemma":[0.002651127,0.01308228,0.05161459,0.0001702858,0.0007233394,0.01205591,0.0001546448,0.006034634,0.591194,0.001568265,0.3207005,0.00005041341],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"other","genre_scores_codex":[0.8388548,0.1048079,0.00447039,0.002614009,0.0009066182,0.0004721769,0.003193832,0.001552421,0.04312794],"genre_scores_gemma":[0.9506444,0.03372283,0.001777276,0.0007162333,0.000164829,0.0001011064,0.001995463,0.00005082786,0.01082711],"genre_candidate":"other","genre_consensus":null,"teacher_disagreement_score":0.003853232,"threshold_uncertainty_score":0.01289034,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01675940992978834,"score_gpt":0.2757411737344744,"score_spread":0.258981763804686,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}