{"id":"W2088630760","doi":"10.1371/journal.pone.0003494","title":"MyD88 Dependent Signaling Contributes to Protective Host Defense against Burkholderia pseudomallei","year":2008,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Burkholderia infections and melioidosis","field":"Medicine","cited_by":69,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"","keywords":"TRIF; Burkholderia pseudomallei; Melioidosis; Innate immune system; Biology; Microbiology; Immune system; Toll-like receptor; Immunology; Signal transducing adaptor protein; Signal transduction; Cell biology; Bacteria","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001662842,0.0003253648,0.0001555676,0.0001264014,0.0001386849,0.0002276635,0.0001456274,0.0003444836,0.00128382],"category_scores_gemma":[0.0001525362,0.0001077072,0.0001319277,0.0000520442,0.0001944273,0.000244511,0.000265,0.0004061154,0.0004213911],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001695838,"about_ca_system_score_gemma":0.0001620205,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009083808,"about_ca_topic_score_gemma":0.0001104281,"domain_scores_codex":[0.9998938,0.00002989397,0.000008691265,0.00001541988,0.00001681231,0.00003533497],"domain_scores_gemma":[0.9999012,0.0000104591,0.00003722099,0.000007391418,0.00001294329,0.0000307941],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004922092,0.00005349669,0.001908118,0.0001261044,0.000004545627,0.0001413209,0.00002434063,0.00009018045,0.9937161,0.0001485362,0.0001534301,0.003141773],"study_design_scores_gemma":[0.0002102997,0.001866342,0.1557761,0.0001497462,0.0001112127,0.004133315,0.000354956,0.006745502,0.814674,0.001050471,0.01490895,0.00001924776],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.990724,0.004542897,0.002556609,0.0003959441,0.00003129043,0.00003370909,0.0002800517,0.00007541365,0.00136013],"genre_scores_gemma":[0.9959103,0.001449086,0.001327985,0.0001146093,0.00001684388,0.00003103138,0.000288164,0.000006439121,0.0008555482],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00128382,"threshold_uncertainty_score":0.004294813,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05664490886105843,"score_gpt":0.2389417091393234,"score_spread":0.182296800278265,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}