{"id":"W2088630760","doi":"10.1371/journal.pone.0003494","title":"MyD88 Dependent Signaling Contributes to Protective Host Defense against Burkholderia pseudomallei","year":2008,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Burkholderia infections and melioidosis","field":"Medicine","cited_by":69,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"","keywords":"TRIF; Burkholderia pseudomallei; Melioidosis; Innate immune system; Biology; Microbiology; Immune system; Toll-like receptor; Immunology; Signal transducing adaptor protein; Signal transduction; Cell biology; Bacteria","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002425999,0.0002648139,0.0005857531,0.0002904706,0.000345137,0.00003241102,0.0001016025,0.00017182,0.0001703562],"category_scores_gemma":[0.0005300306,0.0002493113,0.0001355524,0.0004950563,0.00008008716,0.00009358992,0.0000797898,0.0003404329,0.0003159279],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002081586,"about_ca_system_score_gemma":0.0001495204,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009881053,"about_ca_topic_score_gemma":0.00001301679,"domain_scores_codex":[0.9981254,0.00006079541,0.0004221977,0.0004640422,0.0004520327,0.0004755452],"domain_scores_gemma":[0.9985725,0.00009130558,0.0001040259,0.0004350416,0.0004679492,0.000329234],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004257176,0.002509971,0.01175572,0.0001151679,0.0007637171,0.000173763,0.0006041722,0.00002051631,0.982869,0.00007388079,0.0004405944,0.0002477432],"study_design_scores_gemma":[0.003936721,0.001134655,0.01669756,0.0009279782,0.0005486141,0.0001136772,0.0004094257,0.0001190756,0.9750368,0.0000477982,0.0005996259,0.0004280457],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9902624,0.0002694141,0.001960547,0.001275715,0.0001248614,0.002219753,0.00002603848,0.0002601574,0.003601123],"genre_scores_gemma":[0.9923671,0.0001324349,0.004225506,0.001380715,0.0003560564,0.0006200327,0.00001926852,0.0000583109,0.000840516],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00783222,"threshold_uncertainty_score":0.9999959,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05664490886105843,"score_gpt":0.2389417091393234,"score_spread":0.182296800278265,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}