{"id":"W2088639474","doi":"10.1002/dvdy.20298","title":"Maintenance of gene expression patterns","year":2005,"lang":"en","type":"review","venue":"Developmental Dynamics","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":112,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; National Institutes of Health","keywords":"Biology; Gene silencing; Epigenetics; Genetics; Gene; Polycomb-group proteins; Cell division; Gene expression; Cell biology; Regulation of gene expression; DNA methylation; Computational biology; Cell; Repressor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001213242,0.0002828728,0.0005098052,0.00006984387,0.00003696863,0.00001045153,0.0002546592,0.0003401099,0.00001883477],"category_scores_gemma":[0.00002372072,0.0002493658,0.0002070021,0.00007812268,0.00003396859,0.000001972044,0.000160477,0.0001088519,0.0000115426],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001025135,"about_ca_system_score_gemma":0.000192536,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004164436,"about_ca_topic_score_gemma":0.00003731108,"domain_scores_codex":[0.9987287,0.00004961457,0.0005075284,0.0003635294,0.0001473944,0.0002032579],"domain_scores_gemma":[0.9993195,0.00001000408,0.0003121851,0.0002472227,0.00005147471,0.0000596004],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000004105917,0.0000384253,0.000166789,0.001127898,0.00005340181,0.00000205813,0.00001217388,0.000005109725,0.001719721,0.00001546798,0.0000553243,0.9967995],"study_design_scores_gemma":[0.000150861,0.00004414101,0.00007779991,0.001780703,0.00006025926,0.0000146481,0.00001785685,0.00002510686,0.006928424,0.000008171499,0.9904866,0.0004054408],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001095374,0.9898382,0.00744855,0.000002106531,0.0001721099,0.0002829142,0.0003083771,0.000006931932,0.0008453822],"genre_scores_gemma":[0.0004461604,0.9811144,0.01357995,0.0000101664,0.0001148528,0.00003188333,0.003879437,0.00005268513,0.000770418],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9963941,"threshold_uncertainty_score":0.9999959,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01919781829931069,"score_gpt":0.2914766632334816,"score_spread":0.2722788449341709,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}