{"id":"W2088662513","doi":"10.1016/j.mad.2012.01.004","title":"Effects of aging and caloric restriction on brainstem satiety center signals in rats","year":2012,"lang":"en","type":"article","venue":"Mechanisms of Ageing and Development","topic":"Regulation of Appetite and Obesity","field":"Neuroscience","cited_by":20,"is_retracted":false,"has_abstract":false,"ca_institutions":"Hôpital du Sacré-Cœur de Montréal; Université de Montréal; Centre Hospitalier de l’Université de Montréal","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; National Institutes of Health; Réseau québécois de recherche sur le vieillissement","keywords":"Endocrinology; Internal medicine; Leptin; Caloric theory; Receptor; Glial cell line-derived neurotrophic factor; Calorie restriction; Neurotrophic factors; Energy homeostasis; Biology; Leptin receptor; Medicine; Obesity","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003589237,0.001217174,0.001015321,0.001069466,0.0004496704,0.0004237226,0.0004932912,0.0006024595,0.002462255],"category_scores_gemma":[0.0004416702,0.0005259574,0.0006186285,0.0004107274,0.001596823,0.001052242,0.0005287951,0.001501642,0.000246542],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008102715,"about_ca_system_score_gemma":0.0007476053,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004143972,"about_ca_topic_score_gemma":0.006902567,"domain_scores_codex":[0.9996995,0.00002990413,0.00002638557,0.00008617297,0.0000318267,0.000126366],"domain_scores_gemma":[0.9991593,0.00009864361,0.0002327696,0.000126492,0.00007734235,0.0003055139],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0428909,0.001332322,0.001759606,0.0001219256,0.0000755865,0.0003600309,0.0002318623,0.0002716332,0.9429573,0.0003531405,0.0002039894,0.00944173],"study_design_scores_gemma":[0.000818471,0.01546147,0.05632412,0.00003633604,0.0004066839,0.0003706195,0.0008712437,0.00184722,0.9203332,0.001243827,0.002155267,0.0001316115],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9983075,0.0006129664,0.000336811,0.00008746365,0.00005285945,0.000009510161,0.0002623335,0.0000427492,0.0002878095],"genre_scores_gemma":[0.9930859,0.001166776,0.001057158,0.0001664667,0.00004288637,0.00007977233,0.0005382735,0.00006330824,0.003799506],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004143972,"threshold_uncertainty_score":0.008239746,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01880477050240837,"score_gpt":0.2340922955748898,"score_spread":0.2152875250724814,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}