{"id":"W2088702583","doi":"10.1021/bi050911r","title":"Carboxyl-Terminus Determinants of the Iron Transporter DMT1/SLC11A2 Isoform II (−IRE/1B) Mediate Internalization from the Plasma Membrane into Recycling Endosomes","year":2005,"lang":"en","type":"article","venue":"Biochemistry","topic":"Iron Metabolism and Disorders","field":"Medicine","cited_by":35,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Hospital for Sick Children","funders":"National Institute of Allergy and Infectious Diseases; McGill University","keywords":"Endosome; Internalization; DMT1; Transporter; Cell biology; Chemistry; Gene isoform; Membrane; Biochemistry; Biology; Cell","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001466452,0.000464238,0.0001625923,0.0001646074,0.0001608383,0.0002228919,0.0001980195,0.0002841856,0.001151022],"category_scores_gemma":[0.0001325578,0.0001755777,0.0002237026,0.0001207551,0.0002478838,0.000162706,0.0001990817,0.000439974,0.000676444],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004371285,"about_ca_system_score_gemma":0.0001862956,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000907778,"about_ca_topic_score_gemma":0.001226946,"domain_scores_codex":[0.9998649,0.000023765,0.0000166104,0.00003329126,0.0000388237,0.00002251248],"domain_scores_gemma":[0.999876,0.00002038934,0.00005432292,0.00001104656,0.0000142745,0.00002391099],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004313437,0.000008855978,0.0001536872,0.000012245,0.000001429914,0.0000379674,0.000007380996,0.00002279218,0.9993754,0.00005388695,0.00001336679,0.0002699479],"study_design_scores_gemma":[0.00001915367,0.0000733741,0.00491383,0.000005811589,0.000009481465,0.0005068775,0.00002705455,0.0008290049,0.9916598,0.00002200455,0.001929458,0.000004213844],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9964373,0.0003656787,0.002178388,0.00005729723,0.00001238752,0.00001976112,0.0003039334,0.00002686564,0.0005984056],"genre_scores_gemma":[0.9902563,0.0003897294,0.004998469,0.00004919733,0.000006749538,0.00003649117,0.001044011,0.00004307295,0.003175903],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001151022,"threshold_uncertainty_score":0.003850579,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007371369511935503,"score_gpt":0.2380338912898655,"score_spread":0.23066252177793,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}