{"id":"W2088731817","doi":"10.1039/b904028e","title":"Stabilization of the base-off forms of vitamin B12 and coenzyme B12 by encapsulation of the α-axial 5,6-dimethylbenzimidazole ligand with cucurbit[7]uril","year":2009,"lang":"en","type":"article","venue":"Dalton Transactions","topic":"Porphyrin Metabolism and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":56,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"","keywords":"Chemistry; Ligand (biochemistry); Protonation; Stereochemistry; Cofactor; Heterolysis; Adenosylcobalamin; Crystallography; Hydroxocobalamin; Corrin; Medicinal chemistry; Cobalt; Cyanocobalamin; Inorganic chemistry; Receptor; Ion; Vitamin B12; Organic chemistry; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001132119,0.0001019626,0.0001343777,0.00002651311,0.00008269219,0.00000471543,0.0001157233,0.00006565572,0.00001030982],"category_scores_gemma":[0.00001731995,0.00006275594,0.00007573765,0.0001820575,0.0001564654,0.00001320091,0.000006391586,0.00006112879,8.44455e-8],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000003669581,"about_ca_system_score_gemma":0.00005890193,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005125073,"about_ca_topic_score_gemma":0.0001254976,"domain_scores_codex":[0.9993155,0.00004536149,0.0002276362,0.0001521173,0.0001541933,0.0001051838],"domain_scores_gemma":[0.9994316,0.00001303427,0.0001626537,0.000285003,0.00007822302,0.00002953887],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009919713,0.000163899,0.001301135,0.00003350605,0.0000259448,3.238878e-8,0.0001814505,0.0009186208,0.9945108,0.0001524006,0.0001814898,0.002431581],"study_design_scores_gemma":[0.0007765303,0.0001511007,0.01713111,0.00001809486,0.00007584067,0.000002728049,0.0001540702,0.0002430146,0.980046,0.0001461826,0.001171898,0.00008343155],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9829807,0.0005773777,0.01560074,0.0001783508,0.0000704208,0.0002413302,0.0001808754,0.000003635688,0.000166563],"genre_scores_gemma":[0.9994403,0.0002200152,0.0001535379,0.00005271798,0.00001204271,0.000005769406,0.00004612851,0.00000790721,0.00006156854],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01645961,"threshold_uncertainty_score":0.2559113,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003740064734211618,"score_gpt":0.2001204089410233,"score_spread":0.1963803442068117,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}