{"id":"W2088741171","doi":"10.1074/jbc.m309913200","title":"Determination of Transmembrane Topology of the Escherichia coli Natural Resistance-associated Macrophage Protein (Nramp) Ortholog","year":2004,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Trace Elements in Health","field":"Nursing","cited_by":34,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institut National de la Recherche Scientifique","funders":"Canadian Institutes of Health Research","keywords":"Periplasmic space; Transmembrane domain; Escherichia coli; Membrane topology; Transmembrane protein; Biology; Major facilitator superfamily; Schneider 2 cells; Cytoplasm; Molecular biology; Membrane transport protein; Chemistry; Biochemistry; Topology (electrical circuits); Gene; Transporter","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000111931,0.0001457993,0.0001103502,0.0001335723,0.0001067983,0.0002188046,0.0001527975,0.0002155775,0.0002990402],"category_scores_gemma":[0.0002305241,0.00008474225,0.0001367339,0.00012018,0.00009709725,0.0001373874,0.0001119061,0.0002931246,0.0003043584],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000187358,"about_ca_system_score_gemma":0.0001367384,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003988913,"about_ca_topic_score_gemma":0.0005023566,"domain_scores_codex":[0.9999559,0.00001103819,0.000004254282,0.000008687869,0.00001209101,0.000008086462],"domain_scores_gemma":[0.9999142,0.00002460623,0.00001838516,0.000008610213,0.00001657318,0.00001769534],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000075443,0.00000989142,0.001210816,0.00002654754,0.00000233756,0.0001230566,0.00003430024,0.00033688,0.9970091,0.0001456981,0.00002416817,0.001001807],"study_design_scores_gemma":[0.00001783548,0.0002323754,0.02708638,0.00002067885,0.00002940097,0.001193894,0.0002357617,0.01350239,0.9525963,0.0003162775,0.004747455,0.00002124911],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9962869,0.0001692115,0.002852706,0.00003763173,0.00000407246,0.00000886362,0.0003244527,0.00001901611,0.0002973268],"genre_scores_gemma":[0.9916603,0.0003075395,0.00577344,0.00002181326,0.000002631915,0.000008245189,0.001811796,0.00001036483,0.0004039648],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0003988913,"threshold_uncertainty_score":0.001359344,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01600949777705174,"score_gpt":0.282683307573898,"score_spread":0.2666738097968463,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}