{"id":"W2088747587","doi":"10.1016/j.immuni.2009.06.001","title":"Knocking In the NLRP3 Inflammasome","year":2009,"lang":"en","type":"letter","venue":"Immunity","topic":"Inflammasome and immune disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":false,"ca_institutions":"Canada Research Chairs; University of Toronto","funders":"","keywords":"Inflammasome; Biology; Immunity; Gene; Disease; Mutation; Genetics; Immunology; Immune system; Inflammation; Medicine; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004582969,0.0003170241,0.0002426871,0.0001022928,0.0001546467,0.0000695497,0.001015573,0.0008450582,0.00003238699],"category_scores_gemma":[0.0001135572,0.0002519114,0.0002001663,0.0001582776,0.0000972202,0.000004939487,0.0001516796,0.001894091,0.00005278014],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002089014,"about_ca_system_score_gemma":0.0000995373,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001689931,"about_ca_topic_score_gemma":0.00008860754,"domain_scores_codex":[0.9983071,0.0004138679,0.0003254213,0.0002832922,0.0002064385,0.0004638898],"domain_scores_gemma":[0.9986284,0.00003604438,0.0001356628,0.001130704,0.00005645425,0.00001270824],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00003868096,0.00006325786,0.0004103984,0.00005161535,0.00007182675,0.0001515637,0.0003950398,0.000013897,0.0164539,0.00001419734,0.97473,0.007605624],"study_design_scores_gemma":[0.0003732201,0.0001306114,0.004387903,0.00003712045,0.00001846505,0.0000313336,0.0001399802,0.000001432942,0.003223829,0.0001985716,0.9911147,0.0003428209],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"empirical","genre_gemma":"commentary","genre_scores_codex":[0.5756587,0.007676896,0.00003164651,0.3646988,0.0007635031,0.001043451,0.00003639224,0.00004804219,0.05004263],"genre_scores_gemma":[0.2111873,0.0008056546,0.00004598271,0.7789622,0.002734097,0.00007632609,0.003043988,0.00007612257,0.003068288],"genre_candidate":"commentary","genre_consensus":null,"teacher_disagreement_score":0.4142635,"threshold_uncertainty_score":0.9999933,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01078424339096123,"score_gpt":0.2399136513417635,"score_spread":0.2291294079508022,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}