{"id":"W2088782469","doi":"10.1002/em.20668","title":"Hepatic mRNA, microRNA, and miR‐34a‐Target responses in mice after 28 days exposure to doses of benzo(a)pyrene that elicit DNA damage and mutation","year":2011,"lang":"en","type":"article","venue":"Environmental and Molecular Mutagenesis","topic":"MicroRNA in disease regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":54,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Canada","funders":"Health Canada","keywords":"Benzo(a)pyrene; Toxicogenomics; microRNA; Biology; Molecular biology; Carcinogen; DNA damage; Gene expression; Fold change; Gene; DNA microarray; Microarray; Benzopyrene; DNA; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001164391,0.0002090163,0.0001829425,0.00009760394,0.00004212288,0.00001452948,0.00007287275,0.0001181332,0.00003946812],"category_scores_gemma":[0.00001541002,0.0002161811,0.00004474669,0.00004429199,0.0001393112,0.00001413476,0.000175623,0.00003745108,0.000002780278],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001629449,"about_ca_system_score_gemma":0.00001148787,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004953779,"about_ca_topic_score_gemma":0.00002551513,"domain_scores_codex":[0.998934,0.0001131865,0.0002235953,0.0004273281,0.0001161212,0.0001857728],"domain_scores_gemma":[0.9995643,0.00001106712,0.00008305576,0.000211094,0.00000625106,0.0001242701],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003969808,0.00008700883,0.04151757,0.00005056267,0.00004130976,0.00004760581,0.0005776409,0.000007270944,0.9565434,0.000002484053,0.000008568377,0.000719569],"study_design_scores_gemma":[0.0003644627,0.0001784216,0.4140449,0.00001843236,0.00003510735,0.00001782879,0.0001652762,0.000007572635,0.5849008,0.00002382593,0.00009654948,0.0001468419],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9942406,0.00501661,0.000234026,0.00004094937,0.00002103094,0.0003166988,0.0001063358,0.00000462593,0.00001912274],"genre_scores_gemma":[0.9969443,0.0002968102,0.002289759,0.0002233033,0.00001322676,0.00004584668,0.0001059059,0.00002991543,0.00005093008],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3725273,"threshold_uncertainty_score":0.8815608,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006713481473919868,"score_gpt":0.1985407865406455,"score_spread":0.1918273050667256,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}