{"id":"W2088831597","doi":"10.4161/chan.23898","title":"The topology of the C-terminal sections of the NCX1 Na<sup>+</sup>/Ca<sup>2+</sup>exchanger and the NCKX2 Na<sup>+</sup>/Ca<sup>2+</sup>-K<sup>+</sup>exchanger","year":2013,"lang":"en","type":"article","venue":"Channels","topic":"Plant and Biological Electrophysiology Studies","field":"Agricultural and Biological Sciences","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hotchkiss Brain Institute; Alberta Bible College; University of Calgary","funders":"Canadian Institutes of Health Research","keywords":"Sodium-calcium exchanger; Chemistry; Topology (electrical circuits); Membrane topology; Membrane; C-terminus; Crystal structure; Biophysics; Calcium; Homeostasis; Crystallography; Membrane protein; Intracellular; Biochemistry; Amino acid; Biology; Cell biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001062009,0.0001284612,0.00008220088,0.0001255191,0.000196419,0.0002778955,0.000305521,0.0002739083,0.0008643862],"category_scores_gemma":[0.0002352867,0.00006963537,0.0001118746,0.0001595421,0.0002706125,0.0005363766,0.0001460159,0.0003478462,0.0001770599],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003246908,"about_ca_system_score_gemma":0.0002609551,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001154738,"about_ca_topic_score_gemma":0.001147743,"domain_scores_codex":[0.9999617,0.000004268686,0.000002581175,0.00001465186,0.00001017238,0.000006559212],"domain_scores_gemma":[0.9998939,0.00001560412,0.0000397535,0.000006732103,0.00001952263,0.00002441295],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002272706,0.00001746212,0.001662308,0.00007728115,0.000006044071,0.0001662579,0.00009842531,0.0004174919,0.9937663,0.001345099,0.00009993305,0.002116185],"study_design_scores_gemma":[0.00003837739,0.0002453004,0.09324875,0.00003117104,0.00006343907,0.001739758,0.0004260903,0.01406129,0.8723997,0.001198057,0.01651474,0.00003338295],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9942146,0.0008335426,0.003022203,0.00008244489,0.00001465885,0.00001023279,0.000198047,0.00002490374,0.001599318],"genre_scores_gemma":[0.9913366,0.000849758,0.004320124,0.00004454594,0.00000942832,0.00001992187,0.001189274,0.0000109774,0.002219404],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001154738,"threshold_uncertainty_score":0.00289166,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02022863058495509,"score_gpt":0.2181439346557708,"score_spread":0.1979153040708157,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}