{"id":"W2088883362","doi":"10.1021/ac200575e","title":"DNA Aptamers Binding to Multiple Prevalent M-Types of <i>Streptococcus pyogenes</i>","year":2011,"lang":"en","type":"article","venue":"Analytical Chemistry","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":87,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Water Network; University of Alberta","keywords":"Aptamer; Streptococcus pyogenes; Amplicon; DNA; Chemistry; Polymerase chain reaction; Molecular biology; Population; Pathogen; Microbiology; Bacteria; Biology; Genetics; Biochemistry; Staphylococcus aureus; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000119634,0.0001881325,0.0002386451,0.00003340688,0.00003967827,0.000006899749,0.0002244009,0.0001772346,0.00003261632],"category_scores_gemma":[0.000181486,0.0001680049,0.0002020629,0.0001877684,0.0001398909,0.000002844046,0.0001409968,0.00008132008,0.000007829141],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001676729,"about_ca_system_score_gemma":0.00003370818,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001084833,"about_ca_topic_score_gemma":0.000004430322,"domain_scores_codex":[0.9988304,0.00001634063,0.00030018,0.0004263626,0.0001582901,0.0002684439],"domain_scores_gemma":[0.9991401,0.00001333167,0.00009853016,0.0004627592,0.0001151117,0.0001701665],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007111015,0.000101962,0.007869782,0.00004006355,0.0001075297,0.00000413723,0.00001503687,0.000003297019,0.9902425,0.000006597823,0.0005943023,0.0009436581],"study_design_scores_gemma":[0.0001481604,0.00009705981,0.0004474239,0.00002676481,0.00008724149,0.000005044268,0.0000570424,0.00007012922,0.9957074,0.00001988016,0.003118643,0.0002152293],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9931334,0.00005163921,0.000780772,0.00004108679,0.00001898556,0.0001116268,0.00003281742,0.00003733104,0.005792396],"genre_scores_gemma":[0.9953747,0.00004353296,0.00296674,0.0001103741,0.00008895411,0.000009005385,0.00005412821,0.00002012799,0.001332397],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007422358,"threshold_uncertainty_score":0.685104,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02066111657443295,"score_gpt":0.2678486554614591,"score_spread":0.2471875388870261,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}