{"id":"W2088954563","doi":"10.1152/physiol.00030.2005","title":"Proglucagon-Derived Peptides: Mechanisms of Action and Therapeutic Potential","year":2005,"lang":"en","type":"review","venue":"Physiology","topic":"Diabetes Treatment and Management","field":"Medicine","cited_by":85,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto General Hospital; University of Toronto","funders":"","keywords":"Proglucagon; Hypoglycemia; Glucagon; Glucagon-like peptide-1; Receptor; Glucagon receptor; Glucagon-like peptide-2; Type 2 diabetes; Medicine; Pharmacology; Diabetes mellitus; Endocrinology; Therapeutic approach; Disease; Internal medicine; Biology; Insulin; Peptide; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004780069,0.0002345985,0.00115118,0.0001135959,0.0000232098,0.000003762469,0.00005658868,0.0001524249,0.00008574671],"category_scores_gemma":[0.000004059551,0.0001627203,0.0002296741,0.0000653761,0.00006391545,0.0000193362,0.00005732844,0.0001084088,0.00003665185],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004041889,"about_ca_system_score_gemma":0.00004898458,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004588951,"about_ca_topic_score_gemma":8.610398e-7,"domain_scores_codex":[0.9991933,0.00006147697,0.0002529404,0.0002363292,0.00007578044,0.0001801505],"domain_scores_gemma":[0.9994803,0.00002559768,0.000210023,0.0002166737,0.00002499665,0.00004240393],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00002171666,0.0001571705,1.511384e-7,0.006483341,0.0007304807,0.000002041544,0.0000171879,1.553653e-7,0.003420715,0.0005987466,0.00004672905,0.9885216],"study_design_scores_gemma":[0.00104103,0.001187053,0.0001561434,0.002875396,0.007102204,0.00002419681,0.00005461189,0.00001527784,0.000345672,0.001861406,0.9850618,0.0002752601],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0006793301,0.9977183,0.00005955201,0.0000334345,0.0001681193,0.001019101,0.000005624619,0.00003592196,0.0002806639],"genre_scores_gemma":[0.004922322,0.9937171,0.0003125282,0.00006845769,0.0001682416,0.0001376079,0.0001472098,0.00002970741,0.0004968167],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9882463,"threshold_uncertainty_score":0.6635543,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05746788033207385,"score_gpt":0.3468503597024138,"score_spread":0.28938247937034,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}