{"id":"W2088954563","doi":"10.1152/physiol.00030.2005","title":"Proglucagon-Derived Peptides: Mechanisms of Action and Therapeutic Potential","year":2005,"lang":"en","type":"review","venue":"Physiology","topic":"Diabetes Treatment and Management","field":"Medicine","cited_by":85,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto General Hospital; University of Toronto","funders":"","keywords":"Proglucagon; Hypoglycemia; Glucagon; Glucagon-like peptide-1; Receptor; Glucagon receptor; Glucagon-like peptide-2; Type 2 diabetes; Medicine; Pharmacology; Diabetes mellitus; Endocrinology; Therapeutic approach; Disease; Internal medicine; Biology; Insulin; Peptide; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003158142,0.0008742444,0.001173002,0.00157239,0.000227038,0.0007658968,0.0005026917,0.0008411506,0.003773728],"category_scores_gemma":[0.0002741435,0.0002404367,0.0003217029,0.001542201,0.0004128217,0.001061942,0.0004051354,0.001529876,0.003204696],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003584755,"about_ca_system_score_gemma":0.0005571059,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005296998,"about_ca_topic_score_gemma":0.001027809,"domain_scores_codex":[0.9999036,0.00001690646,0.00001494761,0.00001700384,0.00003693579,0.00001064843],"domain_scores_gemma":[0.9999043,0.00003699815,0.00002003187,0.000003787772,0.00001961091,0.00001529456],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001372348,0.00008206505,0.0001708003,0.007680609,0.00004812692,0.0005275752,0.00004939826,0.0002637919,0.008092701,0.00225609,0.01077158,0.9699201],"study_design_scores_gemma":[0.00004146255,0.0002697758,0.001428368,0.001516523,0.00007778329,0.003961211,0.0001021054,0.00007544106,0.002156334,0.002038881,0.9883112,0.00002073858],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002605378,0.9975703,0.0001686259,0.000168929,0.0001236037,0.00000443177,0.00001687254,0.00001010861,0.001676484],"genre_scores_gemma":[0.001168764,0.9968144,0.0003494433,0.0001650586,0.0001137905,0.000008833251,0.00003311081,0.000001559658,0.001345103],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003773728,"threshold_uncertainty_score":0.01262432,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05746788033207385,"score_gpt":0.3468503597024138,"score_spread":0.28938247937034,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}