{"id":"W2088987774","doi":"10.1038/sj.cdd.4401256","title":"The translation of an antiapoptotic protein HIAP2 is regulated by an upstream open reading frame","year":2003,"lang":"en","type":"article","venue":"Cell Death and Differentiation","topic":"RNA and protein synthesis mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":29,"is_retracted":false,"has_abstract":false,"ca_institutions":"Children's Hospital of Eastern Ontario; University of Ottawa","funders":"Canadian Institutes of Health Research","keywords":"Upstream open reading frame; Open reading frame; Five prime untranslated region; Translation (biology); Biology; Coding region; Untranslated region; Gene; Eukaryotic translation; Translational regulation; Start codon; Messenger RNA; Point mutation; Reporter gene; Cell biology; Genetics; Gene expression; Mutation; Peptide sequence","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002112303,0.0001121867,0.0001039236,0.00001766883,0.0001635698,0.0000903465,0.0001417328,0.0001332155,0.00002172306],"category_scores_gemma":[0.0000187554,0.00008570787,0.00002911719,0.00003998322,0.00002212884,0.00001977163,0.00001639526,0.00003664796,8.036964e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000003731071,"about_ca_system_score_gemma":0.00001934617,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003057225,"about_ca_topic_score_gemma":0.000007543855,"domain_scores_codex":[0.9991872,0.0001669201,0.0001759618,0.0002457678,0.00008801564,0.0001361001],"domain_scores_gemma":[0.999502,0.000009292188,0.0001154058,0.0002665228,0.00004014714,0.00006662367],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006191086,0.00007043378,0.0004060343,0.00001395569,0.00001180348,6.62717e-8,0.0000791312,0.000001798599,0.9878675,0.0004273659,0.00001974221,0.01104028],"study_design_scores_gemma":[0.0004131693,0.0002690539,0.0009695245,0.00001269356,0.00002332516,0.000001112976,0.00005533371,0.0005311294,0.9946289,0.002140715,0.0008409789,0.0001140788],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9907673,0.0004225922,0.007621634,0.00002756821,0.00003560009,0.0004515078,0.00001256084,0.000006402587,0.0006548255],"genre_scores_gemma":[0.9980659,0.0001217364,0.00109881,0.00002527964,0.00001770924,0.00002459511,0.0002019045,0.00001478792,0.0004292373],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01092621,"threshold_uncertainty_score":0.3495066,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01295256559478417,"score_gpt":0.2389933521744222,"score_spread":0.226040786579638,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}