{"id":"W2089016636","doi":"10.1016/j.psyneuen.2007.01.004","title":"Response of the HPA-axis to alcohol and stress as a function of alcohol dependence and family history of alcoholism","year":2007,"lang":"en","type":"article","venue":"Psychoneuroendocrinology","topic":"Stress Responses and Cortisol","field":"Neuroscience","cited_by":83,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University; Douglas Mental Health University Institute","funders":"Canadian Institutes of Health Research; McGill University","keywords":"Alcohol dependence; Alcohol; Family history; Placebo; Psychology; Basal (medicine); Anxiety; Internal medicine; Ethanol; Alcohol abuse; Endocrinology; Ingestion; Hypothalamic–pituitary–adrenal axis; Medicine; Physiology; Psychiatry; Hormone; Chemistry; Insulin","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003080625,0.0002300145,0.0005010353,0.0005476048,0.0003297322,0.0003600042,0.0001891376,0.0002959258,0.001505399],"category_scores_gemma":[0.001773611,0.0002162894,0.0002155199,0.0004412887,0.0005594107,0.0003843564,0.0002808521,0.0007096038,0.0001974151],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000258706,"about_ca_system_score_gemma":0.0002070428,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002419508,"about_ca_topic_score_gemma":0.003348171,"domain_scores_codex":[0.9998368,0.00006767452,0.000007663283,0.00002630442,0.00002430627,0.0000373005],"domain_scores_gemma":[0.998271,0.0005756383,0.0003396993,0.0001119003,0.0001343371,0.0005674054],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.009427215,0.0006008958,0.9563828,0.0000248691,0.0001748943,0.0006038437,0.0005916142,0.0002587252,0.02522521,0.00008411593,0.0001690188,0.006456858],"study_design_scores_gemma":[0.000005323969,0.0002068269,0.9989915,0.000001128301,0.00001127192,0.0001808667,0.00008635966,0.0001205557,0.0003296478,0.00001850251,0.00004502377,0.000003051571],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9992767,0.0002333288,0.00004042027,0.00003237871,0.000004838288,0.000002582464,0.0001011924,0.000004004996,0.0003045193],"genre_scores_gemma":[0.9994029,0.00009101539,0.00004141439,0.00001790857,0.000008077436,0.000004434228,0.00009327778,0.000001992799,0.0003389855],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002419508,"threshold_uncertainty_score":0.005036056,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04556309742868966,"score_gpt":0.3047527884766473,"score_spread":0.2591896910479577,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}