{"id":"W2089060011","doi":"10.1371/journal.pone.0005601","title":"Lipoteichoic Acid Induces Unique Inflammatory Responses when Compared to Other Toll-Like Receptor 2 Ligands","year":2009,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Immune Response and Inflammation","field":"Immunology and Microbiology","cited_by":78,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"Natural Sciences and Engineering Research Council of Canada; Alberta Heritage Foundation for Medical Research","keywords":"Lipoteichoic acid; TLR2; In vivo; Cell biology; Biology; Receptor; Toll-like receptor; Ligand (biochemistry); Signal transduction; Stimulation; TLR4; Innate immune system; Biochemistry; Neuroscience; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0004424148,0.0002470882,0.0004201325,0.0003094031,0.0002072376,0.00003993418,0.0003322921,0.0003502994,0.0008233315],"category_scores_gemma":[0.0002807557,0.0002351742,0.00007738651,0.0001750528,0.00007603421,0.0002254942,0.00006230477,0.0003349705,0.002985907],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007510838,"about_ca_system_score_gemma":0.0001191303,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002164943,"about_ca_topic_score_gemma":0.00001484357,"domain_scores_codex":[0.9983758,0.000344908,0.0004527805,0.0003162455,0.00009251929,0.0004177163],"domain_scores_gemma":[0.9990252,0.0001482323,0.0001437479,0.0004915901,0.0001402859,0.00005091221],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002055513,0.0004277369,0.0003901305,0.00001648843,0.0002569452,0.000003323185,0.001834602,0.000001101871,0.9872822,0.0001763646,0.005816365,0.001739203],"study_design_scores_gemma":[0.0008362855,0.0004508259,0.005141468,0.000230492,0.00005564589,0.000006807933,0.0001243758,0.000001489624,0.9522558,0.0001406977,0.04046642,0.000289728],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9936964,0.001266512,0.00003158407,0.002788862,0.0001897086,0.0005011684,0.00001516364,0.0002378219,0.001272806],"genre_scores_gemma":[0.9836303,0.00008277369,0.0005772614,0.001743398,0.0001091131,0.00005694386,0.00007373946,0.0000285917,0.01369785],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03502646,"threshold_uncertainty_score":0.9977904,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03186295625109466,"score_gpt":0.2368854039283902,"score_spread":0.2050224476772955,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}