{"id":"W2089068194","doi":"10.1074/jbc.m114.567388","title":"Substrate Specificity and Kinetic Characterization of Peptidoglycan O-Acetyltransferase B from Neisseria gonorrhoeae","year":2014,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Bacterial Genetics and Biotechnology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph","funders":"Canadian Institutes of Health Research; University of Washington","keywords":"Peptidoglycan; Microbiology; Cell wall; Bacterial outer membrane; Cell envelope; Neisseria gonorrhoeae; Bacterial cell structure; Biology; Neisseria; Bacillus anthracis; Bacteria; Virulence factor; Biochemistry; Virulence; Escherichia coli","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001583424,0.0001522325,0.000289642,0.00001725395,0.00002473458,0.00001652072,0.0001986241,0.0003823069,0.00006348263],"category_scores_gemma":[0.00008256662,0.0001161772,0.00009397657,0.00005472912,0.0001845308,0.000003237611,0.00005550284,0.0001516357,5.847104e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000005856375,"about_ca_system_score_gemma":0.00002563003,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004257409,"about_ca_topic_score_gemma":0.000001919896,"domain_scores_codex":[0.9991215,0.00004432285,0.0004309033,0.0002111347,0.0000413932,0.0001507426],"domain_scores_gemma":[0.999298,0.00001536435,0.0003019717,0.0001774631,0.0001095789,0.00009758049],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002265436,0.00006011923,0.005238652,0.00001559923,0.00003196946,7.5772e-7,0.000007320537,0.000001542665,0.9929265,0.00001014261,0.00001012034,0.001470746],"study_design_scores_gemma":[0.000473926,0.0004994529,0.05535674,0.00001806012,0.00001800629,0.00004312762,0.00002131062,0.00001109402,0.9383101,0.00009066876,0.005030005,0.000127488],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9988222,0.0001574622,0.0005990333,0.0001416778,0.00009060014,0.00004392489,0.00005106381,0.00000433873,0.00008974745],"genre_scores_gemma":[0.9980184,0.000776449,0.000540899,0.00004831438,0.0004797943,9.501359e-7,0.000107723,0.000008873094,0.00001859542],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05461637,"threshold_uncertainty_score":0.473757,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01029380603403143,"score_gpt":0.2066673075537258,"score_spread":0.1963735015196944,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}