{"id":"W2089089273","doi":"10.1016/j.jsbmb.2009.05.005","title":"Analysis of 17β-hydroxysteroid dehydrogenase types 5, 7, and 12 genetic sequence variants in breast cancer cases from French Canadian Families with high risk of breast and ovarian cancer","year":2009,"lang":"en","type":"article","venue":"The Journal of Steroid Biochemistry and Molecular Biology","topic":"Estrogen and related hormone effects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université Laval","funders":"Canadian Breast Cancer Research Alliance; Breast Cancer Alliance","keywords":"Missense mutation; Breast cancer; Biology; Genetics; Cancer; Gene; Cancer research; Mutation","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003154763,0.000728563,0.0004440937,0.00414469,0.002612532,0.0006999549,0.000880913,0.0006695317,0.003725901],"category_scores_gemma":[0.001542342,0.0004233765,0.0006770016,0.003168079,0.0007225131,0.0001271904,0.0004078224,0.0004540285,0.0002452261],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00434652,"about_ca_system_score_gemma":0.004043163,"about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_topic_score_codex":0.9013982,"about_ca_topic_score_gemma":0.8525418,"domain_scores_codex":[0.9993219,0.00005913754,0.00004793124,0.0001260698,0.0002362411,0.0002087323],"domain_scores_gemma":[0.9993809,0.0001283853,0.00008828913,0.00002296687,0.0002288939,0.0001505079],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0006655405,0.00009196542,0.9557804,0.00006248953,0.0001852738,0.01350369,0.003823198,0.0003192948,0.01517933,0.0003830431,0.001173636,0.008831982],"study_design_scores_gemma":[0.00003316137,0.00006106288,0.985685,0.00003720774,0.000146635,0.007831702,0.002033092,0.00038994,0.001280707,0.00005873255,0.002417396,0.0000252346],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9968272,0.0003799128,0.0001652899,0.0001296921,0.00001289393,0.00002507786,0.0009437373,0.000009335107,0.001506765],"genre_scores_gemma":[0.9979084,0.0003028053,0.0002273537,0.00005439142,0.000007431445,0.00001234844,0.0004480585,0.000006843668,0.00103247],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.09860182,"threshold_uncertainty_score":0.198365,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003521765718979208,"score_gpt":0.2194907258619238,"score_spread":0.2159689601429446,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}