{"id":"W2089152570","doi":"10.1590/s0100-879x2011007500002","title":"Construction of a recombinant adenovirus co-expressing truncated human prostate-specific membrane antigen and mouse 4-1BBL genes and its effect on dendritic cells","year":2011,"lang":"en","type":"article","venue":"Brazilian Journal of Medical and Biological Research","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Directorate for Biological Sciences; Wuhan University; University of Toronto; National Natural Science Foundation of China; Clemson University","keywords":"CD80; CD86; Molecular biology; Biology; Recombinant DNA; Flow cytometry; Multiplicity of infection; Antigen; Dendritic cell; Viral vector; Transfection; Virology; Immunology; CD40; T cell; Cell culture; Gene; Immune system; Cytotoxic T cell; Virus; In vitro","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003842944,0.0004809524,0.000433216,0.0002967109,0.0001932196,0.0004025178,0.0003580473,0.0003522875,0.001021667],"category_scores_gemma":[0.0001942533,0.0002962021,0.0004129123,0.0002427956,0.0002855838,0.0002496475,0.0002717962,0.0008753813,0.0006357812],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005628944,"about_ca_system_score_gemma":0.0004172627,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007154376,"about_ca_topic_score_gemma":0.0004549738,"domain_scores_codex":[0.9996221,0.00007409137,0.00005493714,0.00008594988,0.00008949894,0.0000733647],"domain_scores_gemma":[0.9998239,0.00003483866,0.00003912264,0.00003388356,0.0000225211,0.00004576077],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001599645,0.00005412564,0.0002022942,0.00007410011,0.000009746105,0.00005031995,0.00002810539,0.000136484,0.9977216,0.0003607222,0.00004845452,0.001153989],"study_design_scores_gemma":[0.00007472351,0.0005063332,0.001056506,0.00001403083,0.00004808922,0.0003396774,0.00003713571,0.002074064,0.9874848,0.0000852299,0.008269223,0.0000101776],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9648232,0.00210656,0.02883484,0.0002243261,0.0002159594,0.0003266667,0.001548646,0.000174695,0.001745063],"genre_scores_gemma":[0.9468377,0.00168657,0.04106819,0.00008253763,0.00003263055,0.0003183659,0.00349669,0.00006828093,0.00640912],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001021667,"threshold_uncertainty_score":0.00408411,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08215775384486872,"score_gpt":0.340612393167377,"score_spread":0.2584546393225082,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}