{"id":"W2089195565","doi":"10.1002/cncr.20168","title":"Oral topotecan in children with recurrent or progressive high‐grade glioma","year":2004,"lang":"en","type":"article","venue":"Cancer","topic":"Glioma Diagnosis and Treatment","field":"Medicine","cited_by":23,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"Deutsche Kinderkrebsstiftung","keywords":"Topotecan; Medicine; Pharmacokinetics; Glioma; Toxicity; Gastroenterology; Surgery; Internal medicine; Chemotherapy; Anesthesia","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00002347544,0.000138014,0.0002243424,0.00009344365,0.00002972616,0.00001303399,0.00004772747,0.00004697772,0.0002249935],"category_scores_gemma":[0.0000083174,0.000082002,0.00003322044,0.0003144368,0.00005624455,0.00004070648,0.00001532436,0.0001003418,0.00001455088],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003977467,"about_ca_system_score_gemma":0.000232292,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001104762,"about_ca_topic_score_gemma":0.001107821,"domain_scores_codex":[0.9992174,0.000009909105,0.0001212225,0.0002436006,0.0001713457,0.000236524],"domain_scores_gemma":[0.999617,0.000005971842,0.00004967244,0.0001752158,0.00003747803,0.0001146775],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0009110636,0.00205973,0.9166172,0.00004386934,0.0004121192,0.001929616,0.0004601035,0.000172504,0.0004999848,0.00062411,0.0008590916,0.07541064],"study_design_scores_gemma":[0.01145692,0.001221808,0.9621433,0.0006055831,0.0001514619,0.0002924756,0.00003803645,0.000002910846,0.02305438,0.0001168954,0.0007470163,0.0001691933],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9939784,0.002462912,0.000002050662,0.002648589,0.00008746234,0.0006967843,0.00001937113,0.00003552082,0.00006893064],"genre_scores_gemma":[0.9985063,0.0001178973,0.0005065358,0.0002007068,0.0001269242,0.000462056,0.00002595568,0.00001939492,0.00003419847],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07524145,"threshold_uncertainty_score":0.3343945,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01835975801624504,"score_gpt":0.307219139205276,"score_spread":0.288859381189031,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}