{"id":"W2089199573","doi":"10.1385/mn:31:1-3:017","title":"Role of Mitochondrial Dysfunction and Oxidative Stress in the Pathogenesis of Selective Neuronal Loss in Wernicke's Encephalopathy","year":2005,"lang":"en","type":"review","venue":"Molecular Neurobiology","topic":"Alcoholism and Thiamine Deficiency","field":"Medicine","cited_by":74,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Montréal; Hôpital Saint-Luc","funders":"Canadian Institutes of Health Research","keywords":"Oxidative stress; Pathogenesis; Neurology; Neuroscience; Mitochondrion; Wernicke Encephalopathy; Encephalopathy; Medicine; Wernicke's encephalopathy; Biology; Pathology; Internal medicine; Thiamine; Cell biology; Thiamine deficiency","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005524826,0.0008118307,0.001789217,0.001755946,0.0002689248,0.0008677585,0.001237548,0.00129043,0.00178936],"category_scores_gemma":[0.0004655504,0.0002193914,0.0003168837,0.001831279,0.0004854126,0.001243001,0.000499017,0.001130332,0.001368242],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005751416,"about_ca_system_score_gemma":0.0009011865,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001362823,"about_ca_topic_score_gemma":0.002408175,"domain_scores_codex":[0.9998864,0.00001875615,0.00002391465,0.00001946389,0.00004059227,0.00001081082],"domain_scores_gemma":[0.9997815,0.00007370266,0.00004270785,0.000006804506,0.00006382036,0.00003155007],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002279521,0.00008683986,0.0004199151,0.01301915,0.0001394051,0.001322591,0.00006905284,0.0004114964,0.003128281,0.002001883,0.02468517,0.9544883],"study_design_scores_gemma":[0.00008382177,0.000187789,0.003089637,0.00342844,0.0003533688,0.00846258,0.0001778504,0.0002097865,0.001071286,0.002898005,0.9799947,0.00004276439],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001631036,0.9990181,0.0001157434,0.0001740913,0.0001546619,0.000002437495,0.000007344343,0.000004210433,0.0003604453],"genre_scores_gemma":[0.0008207386,0.998328,0.0001655482,0.00008711282,0.0002074591,0.000003027781,0.00001665291,4.647674e-7,0.0003710066],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.00178936,"threshold_uncertainty_score":0.005986035,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01481513977389548,"score_gpt":0.2824667568215238,"score_spread":0.2676516170476284,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}