{"id":"W2089215521","doi":"10.1139/w07-018","title":"Site-directed mutagenesis studies to probe the role of specific residues in the external loop (L3) of OmpF and OmpC porins in susceptibility of<i>Serratia marcescens</i>to antibiotics","year":2007,"lang":"en","type":"article","venue":"Canadian Journal of Microbiology","topic":"Antibiotic Resistance in Bacteria","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"Natural Sciences and Engineering Research Council of Canada; University of Manitoba","keywords":"Porin; Serratia marcescens; Bacterial outer membrane; Biology; Biochemistry; Enterobacteriaceae; Microbiology; Amino acid; Methionine; Escherichia coli; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003700404,0.0004656687,0.0003717311,0.0001940332,0.0001937618,0.0001915025,0.0003731425,0.0004140587,0.0007843318],"category_scores_gemma":[0.0004214128,0.0001599711,0.0006259975,0.0002081542,0.000264159,0.000114593,0.0002091459,0.0005244321,0.0002752935],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003480868,"about_ca_system_score_gemma":0.0003120152,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001736816,"about_ca_topic_score_gemma":0.001721659,"domain_scores_codex":[0.9997581,0.00007669818,0.00003563605,0.00003189773,0.00005570507,0.00004202718],"domain_scores_gemma":[0.9995452,0.000139081,0.0001424662,0.00003690696,0.00005437988,0.00008203055],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004294651,0.0002003059,0.0009919222,0.00004237627,0.00002062298,0.0002578312,0.00004497786,0.0005010929,0.9965433,0.0001024381,0.00002985159,0.0008356759],"study_design_scores_gemma":[0.000167399,0.001911475,0.01392058,0.00002380372,0.000120108,0.001049863,0.0001329639,0.005217079,0.9756315,0.00008286189,0.001714545,0.00002777575],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9973775,0.0001298807,0.001821991,0.00004515051,0.00001663927,0.00006764779,0.0001753385,0.00002408466,0.0003417041],"genre_scores_gemma":[0.996474,0.0001012865,0.002622691,0.00005748193,0.000007711737,0.0000337796,0.0002865907,0.00002027346,0.000396217],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001736816,"threshold_uncertainty_score":0.003453434,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0119755000086919,"score_gpt":0.2503458488614146,"score_spread":0.2383703488527227,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}