{"id":"W2089224685","doi":"10.1016/j.peptides.2005.03.019","title":"Development and pharmacological characterization of “caged” urotensin II analogs","year":2005,"lang":"en","type":"article","venue":"Peptides","topic":"Cardiovascular, Neuropeptides, and Oxidative Stress Research","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université du Québec à Montréal; Institut National de la Recherche Scientifique","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Peptide; Urotensin-II; Chemistry; Biological activity; Cyclic peptide; Amino acid; Receptor; Intracellular; Stereochemistry; Biochemistry; In vitro","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002329299,0.0001105955,0.0002756306,0.0001096504,0.000102003,0.00001152154,0.00004900202,0.00004218765,0.0001463958],"category_scores_gemma":[0.0000971344,0.0000882447,0.00007684362,0.0001390759,0.0001353069,0.00008246119,0.0001008807,0.0001420115,0.0000186251],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003183989,"about_ca_system_score_gemma":0.00005498366,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00000553479,"about_ca_topic_score_gemma":0.000004744696,"domain_scores_codex":[0.9989944,0.00006103574,0.0002289786,0.0002239112,0.0003024422,0.0001892939],"domain_scores_gemma":[0.9995315,0.00003130897,0.00004983218,0.0001199442,0.0001489874,0.000118424],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001213889,0.0001238494,0.004181306,0.00005502484,0.0001422451,0.00003678143,0.0004604088,0.000002879602,0.8436062,0.00002680121,0.000166333,0.1510767],"study_design_scores_gemma":[0.001083435,0.00014483,0.410787,0.00006210865,0.00007291482,0.00004995304,0.00005347092,0.0001426736,0.4941864,0.000002594899,0.09330416,0.0001105233],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9970221,0.0002106144,0.0002012447,0.0003787695,0.00002786312,0.0002539478,0.000005815395,0.00003106989,0.001868608],"genre_scores_gemma":[0.9952222,0.000442847,0.00277843,0.0002568344,0.00018037,0.00001291677,0.00003942612,0.00001270826,0.001054275],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4066057,"threshold_uncertainty_score":0.3598514,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03729769131324711,"score_gpt":0.3043684744118463,"score_spread":0.2670707830985992,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}