{"id":"W2089225284","doi":"10.1021/bi800402q","title":"Trafficking and Intracellular ATPase Activity of Human Ecto-nucleotidase NTPDase3 and the Effect of ER-Targeted NTPDase3 on Protein Folding","year":2008,"lang":"en","type":"article","venue":"Biochemistry","topic":"Adenosine and Purinergic Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval; Centre hospitalier universitaire de Québec","funders":"Canadian Institutes of Health Research; National Heart, Lung, and Blood Institute; Universität Heidelberg; Johns Hopkins University","keywords":"Endoplasmic reticulum; Golgi apparatus; Brefeldin A; Cell biology; Secretory pathway; ATP hydrolysis; Biochemistry; Biology; ER retention; Chemistry; ATPase; Mutant; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002613909,0.000288052,0.0003127989,0.0001152147,0.0001823165,0.0003670834,0.0002378413,0.0003924355,0.0008495382],"category_scores_gemma":[0.0002670697,0.0001880662,0.0004142194,0.0002918282,0.0003717595,0.0002606691,0.0001388682,0.0006388333,0.0003746161],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006549806,"about_ca_system_score_gemma":0.0002841468,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002215693,"about_ca_topic_score_gemma":0.001577871,"domain_scores_codex":[0.9997054,0.00005483933,0.00004905598,0.00005738585,0.0000554326,0.00007787762],"domain_scores_gemma":[0.9998272,0.00005626167,0.00002997825,0.00002517157,0.00002285036,0.00003843202],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001000582,0.0001269161,0.0002236241,0.00003227389,0.000009756775,0.0001113704,0.00003375453,0.00009768753,0.9973832,0.0001292695,0.0000710738,0.0007805681],"study_design_scores_gemma":[0.00009538478,0.0004157964,0.00437653,0.000003672293,0.00001858024,0.0003221884,0.00003165903,0.002598511,0.9904405,0.00005903944,0.001630782,0.000007295694],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9975925,0.000838411,0.0005734977,0.00009251798,0.00002866946,0.00001288779,0.0004014125,0.00001536443,0.0004446173],"genre_scores_gemma":[0.9952247,0.0007637186,0.001177144,0.00005409053,0.00001576035,0.00003101588,0.001251212,0.00002157104,0.001460819],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002215693,"threshold_uncertainty_score":0.004752219,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00632765418976796,"score_gpt":0.2214660401856834,"score_spread":0.2151383859959154,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}