{"id":"W2089324774","doi":"10.1016/j.jaci.2013.07.052","title":"Primary Immune Deficiency Treatment Consortium (PIDTC) report","year":2013,"lang":"en","type":"article","venue":"Journal of Allergy and Clinical Immunology","topic":"Immunodeficiency and Autoimmune Disorders","field":"Immunology and Microbiology","cited_by":86,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Centre Hospitalier Universitaire Sainte-Justine","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute of Neurological Disorders and Stroke; National Cancer Institute; National Heart, Lung, and Blood Institute; Manton Center for Orphan Disease Research, Boston Children's Hospital; Feinberg School of Medicine; University of California, San Francisco; Harvard Stem Cell Institute; Baxter Healthcare Corporation; National Institutes of Health; National Center for Advancing Translational Sciences; Bentham-Moxon Trust; University of California, Los Angeles; Medac; University of Toronto; University of Southern California; Wellcome Trust; University College London; Children's Hospital Los Angeles; CSL Behring; National Institute for Health and Care Research; Towson University; University of South Florida; University of Washington; Perelman School of Medicine, University of Pennsylvania; Immune Deficiency Foundation; Texas Children's Hospital; Universität Zürich; School of Medicine; Newcastle University; University of Pennsylvania; Hospital for Sick Children; School of Medicine, Duke University; Northwestern University; NIH Clinical Center; National Institute of Allergy and Infectious Diseases; Grifols; Children's Hospital of Philadelphia; bluebird bio; Cincinnati Children's Hospital Medical Center; March of Dimes Foundation","keywords":"Primary immunodeficiency; Medicine; Family medicine; Severe combined immunodeficiency; Transplantation; Natural history; Pediatrics; Disease; Pathology; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.007714956,0.0004982086,0.0004935189,0.001037595,0.001656766,0.003247917,0.001300664,0.002744769,0.01839637],"category_scores_gemma":[0.01095977,0.0002451946,0.0006994188,0.001440418,0.0004818166,0.001234619,0.002446672,0.003310352,0.004092479],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0023893,"about_ca_system_score_gemma":0.0143625,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.006872192,"about_ca_topic_score_gemma":0.007076767,"domain_scores_codex":[0.9932743,0.001491922,0.0007908623,0.0004776531,0.002942209,0.001023056],"domain_scores_gemma":[0.9834252,0.001585051,0.001161708,0.001169143,0.006881119,0.005777846],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000138454,0.0002023526,0.01562903,0.0001773871,0.00004596481,0.0008632719,0.00007438943,0.0001198698,0.0002490946,0.002383977,0.9225605,0.05755572],"study_design_scores_gemma":[0.0001925202,0.0001835237,0.0202968,0.0004345522,0.00004893603,0.002089303,0.0001886151,0.0002286286,0.000477618,0.0009228269,0.9749074,0.00002934671],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"other","genre_gemma":"other","genre_scores_codex":[0.04531719,0.0429952,0.02191466,0.3595726,0.06873588,0.006884687,0.05250075,0.002484153,0.3995948],"genre_scores_gemma":[0.3167468,0.04384988,0.03783453,0.1685435,0.03759966,0.01013277,0.1775976,0.001405298,0.2062899],"genre_candidate":"other","genre_consensus":"other","teacher_disagreement_score":0.01839637,"threshold_uncertainty_score":0.06154203,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01687772913197621,"score_gpt":0.2781151798444145,"score_spread":0.2612374507124383,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}